Protein Alignment Ser12 and GZMK

DIOPT Version :10

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_002095.1
• Gene: GZMK / 3003
• HGNCID: 4711
• Length: 264
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 79/256 - (30%)
• Similarity: 128/256 - (50%)
• Gaps: 30/256 - (11%)

  Fly     3 LHWLVLVASVTLISAGSSPERIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAHCVE 67
            |.:|::.|.:|.:....   .|:||..|.....|:.|::.|...::||.|:...:.::|||||..
Human     9 LFFLIVGAYMTHVCFNM---EIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQY 70

  Fly    68 R------PFDTLYSVRVG--SVWKNLGGQHARVAVIRKHEDY--VSSTILFNDIAVIRLVDTLIF 122
            |      |     :|.:|  |:.||...:  :...|:|...:  |:|....|||.:::|......
Human    71 RFTKGQSP-----TVVLGAHSLSKNEASK--QTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKL 128

  Fly   123 NAEVRPIQL-ADSAPAAGTEASVSGWGEIGILWLQPTSLLK-TSVKILDPNVC-KRSY----QYI 180
            |..|:.:.: :.::..:||:..|:|||......|:|:..|: .:|.:|...:| .:||    .:|
Human   129 NKHVKMLHIRSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFI 193

  Fly   181 TKTMICA--AALLKDSCHGDSGGPLVSGGQLVGIVSYGIGCANPFFPGVYANVA-ELKPWI 238
            ||.|:||  |...||||.|||||||:..|....|||.|..|.....||:|..:. :.:.||
Human   194 TKDMVCAGDAKGQKDSCKGDSGGPLICKGVFHAIVSGGHECGVATKPGIYTLLTKKYQTWI 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	73/234 (31%)
GZMK	NP_002095.1	Tryp_SPc	27..257	CDD:238113	75/235 (32%)