DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ser12 and KLK9

DIOPT Version :9

Sequence 1:NP_523456.1 Gene:Ser12 / 33406 FlyBaseID:FBgn0011832 Length:245 Species:Drosophila melanogaster
Sequence 2:NP_036447.1 Gene:KLK9 / 284366 HGNCID:6370 Length:250 Species:Homo sapiens


Alignment Length:249 Identity:82/249 - (32%)
Similarity:131/249 - (52%) Gaps:16/249 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 VLVASVTLISA-GSSPERIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAHCVERPF 70
            :|.|.::|::. |.:..|.:|......:..||||.|.:..:..|||.:.||:.::||||| .:|:
Human     5 LLCALLSLLAGHGWADTRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAHC-RKPY 68

  Fly    71 DTLYSVRVGS--VWKNLGGQHA-RVAVIRKHEDY---VSSTILFNDIAVIRLVDTLIFNAEVRPI 129
              |: ||:|.  :||..|.:.. ||.....|..:   :|:....:||.:|||......:..|:|:
Human    69 --LW-VRLGEHHLWKWEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARLSPAVQPL 130

  Fly   130 QLADSAPAAGTEASVSGWGEIGI-LWLQPTSLLKTSVKILDPNVCKRSYQ-YITKTMICAAALL- 191
            .|:.:..:.|.:..:||||.:.. ..|.|.:|...::.||:..:|..:|. :|:.:|:||.... 
Human   131 NLSQTCVSPGMQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHISDSMLCAGLWEG 195

  Fly   192 -KDSCHGDSGGPLVSGGQLVGIVSYGI-GCANPFFPGVYANVAELKPWILNAIE 243
             :.||.||||||||..|.|.|:||.|. .|:.|..|.||.:|.....||...:|
Human   196 GRGSCQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWIQEIME 249

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ser12NP_523456.1 Tryp_SPc 23..238 CDD:214473 75/225 (33%)
Tryp_SPc 24..238 CDD:238113 74/224 (33%)
KLK9NP_036447.1 Tryp_SPc 24..247 CDD:238113 76/226 (34%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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