Protein Alignment Ser12 and KLK5

DIOPT Version :10

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 80/246 - (32%)
• Similarity: 120/246 - (48%)
• Gaps: 40/246 - (16%)

  Fly    20 SPERIVGGHPVLISEVPWQAALMYSEKYI-CGAVIYSDKIIITAAHCVERPFDTLYSVRVGSVWK 83
            |..||:.|....:...||||||:.....: ||||:...:.::|||||.::    ::.||:|
Human    63 SSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKK----VFRVRLG---- 119

  Fly    84 NLGGQHARVAVIRKHEDYVSSTILF-----------------NDIAVIRLVDTLIFNAEVRPIQL 131
                 |..::.:     |.|...:|                 ||:.:|:|...:....:||||.:
Human   120 -----HYSLSPV-----YESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINV 174

  Fly   132 ADSAPAAGTEASVSGWGEIGILWLQ-PTSLLKTSVKILDPNVCKRSY-QYITKTMICAAALL-KD 193
            :...|:|||:..|||||......:. |..|...::.:|....|:.:| :.|..||.||.... :|
Human   175 SSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRD 239

  Fly   194 SCHGDSGGPLVSGGQLVGIVSYG-IGCANPFFPGVYANVAELKPWILNAIE 243
            ||.||||||:|..|.|.|:||:| ..||.|..||||.|:.:...||...|:
Human   240 SCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	76/236 (32%)
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		2/4 (50%)
		Tryp_SPc	66..285	CDD:214473	76/236 (32%)