Protein Alignment Ser12 and TPSD1

DIOPT Version :10

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_036349.1
• Gene: TPSD1 / 23430
• HGNCID: 14118
• Length: 242
• Species: Homo sapiens
• Alignment Length: 239
• Identity: 68/239 - (28%)
• Similarity: 111/239 - (46%)
• Gaps: 48/239 - (20%)

  Fly     1 MLLHWLVLVASVTLI--SAGSSPER--IVGGHPVLISEVPWQAALMYSEKY---ICGAVIYSDKI 58
            :||..|.::||...:  :.|.:.::  ||||.....|:.|||.:|.....|   .||..:...:.
Human    11 LLLLALPVLASPAYVAPAPGQALQQTGIVGGQEAPRSKWPWQVSLRVRGPYWMHFCGGSLIHPQW 75

  Fly    59 IITAAHCVERPFDTLYSVRVGSVWKNLGGQH----------ARVAVIRKH-EDYVSSTILFNDIA 112
            ::|||||||.....|.::||     .|..||          :|:.|   | :.|:..|  ..|||
Human    76 VLTAAHCVEPDIKDLAALRV-----QLREQHLYYQDQLLPVSRIIV---HPQFYIIQT--GADIA 130

  Fly   113 VIRLVDTLIFNAEVRPIQLADSAPAA-----GTEASVSGWGEI--GILWLQPTSLLKTSVKILDP 170
            ::.|.:.:..::.:..:.|   .||:     |....|:|||::  .:....|..|.:..|.:::.
Human   131 LLELEEPVNISSHIHTVTL---PPASETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEVPVVEN 192

  Fly   171 NVCK----------RSYQYITKTMICAAALLKDSCHGDSGGPLV 204
            ::|.          .|:|.:...|:||.:...|||.||||||||
Human   193 HLCNAEYHTGLHTGHSFQIVRDDMLCAGSENHDSCQGDSGGPLV 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	62/215 (29%)
TPSD1	NP_036349.1	Tryp_SPc	38..242	CDD:238113	62/212 (29%)