Protein Alignment Ser12 and PRSS55

DIOPT Version :10

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: XP_047277448.1
• Gene: PRSS55 / 203074
• HGNCID: 30824
• Length: 376
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 76/241 - (31%)
• Similarity: 111/241 - (46%)
• Gaps: 37/241 - (15%)

  Fly    23 RIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAHCV--ERPFDTLYSVRVGSVWKNL 85
            ||.||....:.|.|||.::....:..||..|.:...|:|||||:  |..|....||.:|:  .:|
Human    91 RITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGT--NDL 153

  Fly    86 GG---QHARVAVIRKHEDYVSSTILFNDIAVIRLVDTLIFNAEVRPIQLAD----------SAPA 137
            ..   :...||.|..|:|:..:. :.||||::.|..         ||:|.|          ..||
Human   154 TSPSMEIKEVASIILHKDFKRAN-MDNDIALLLLAS---------PIKLDDLKVPICLPTQPGPA 208

  Fly   138 AGTEASVSGWGEIGILWLQ--PTSLLKTSVKILDPNVCKRSYQYITKTMICAAALLK--DSCHGD 198
            ...|..|:|||:.......  .|.|:|..:.|:|...|.:.:..:||.|:||....:  |:|.||
Human   209 TWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPKLTKNMLCAGYKNESYDACKGD 273

  Fly   199 SGGPLVSGGQ------LVGIVSYGIGCANPFFPGVYANVAELKPWI 238
            ||||||...:      .|||:|:|..|.....||:|.::.....||
Human   274 SGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWI 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	74/239 (31%)
PRSS55	XP_047277448.1	Tryp_SPc	92..322	CDD:238113	75/240 (31%)