Protein Alignment Ser12 and Plg

DIOPT Version :10

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_032903.3
• Gene: Plg / 18815
• MGIID: 97620
• Length: 812
• Species: Mus musculus
• Alignment Length: 281
• Identity: 83/281 - (29%)
• Similarity: 119/281 - (42%)
• Gaps: 84/281 - (29%)

  Fly     8 LVASVTLISAG-------SSPERIVGGHPVLISEVPWQAAL--MYSEKYICGAVIYSDKIIITAA 63
            |.||.:....|       ..|.|:|||........|||.:|  .::.::.||..:.:.:.::|||
Mouse   559 LCASASSFECGKPQVEPKKCPGRVVGGCVANPHSWPWQISLRTRFTGQHFCGGTLIAPEWVLTAA 623

  Fly    64 HCVE---RPFDTLYSVRVGSVWKNLGGQHARVAVIRKHEDY----------VSSTIL---FNDIA 112
            ||:|   ||  ..|.|.:|:                 ||:|          |:..||   ..|||
Mouse   624 HCLEKSSRP--EFYKVILGA-----------------HEEYIRGLDVQEISVAKLILEPNNRDIA 669

  Fly   113 VIRLVDTLIFNAEVRPIQLADSA-PAA----------GTEASVSGWGEIGILWLQPT----SLLK 162
            :::|         .||..:.|.. ||.          .|...::||||     .|.|    .|.:
Mouse   670 LLKL---------SRPATITDKVIPACLPSPNYMVADRTICYITGWGE-----TQGTFGAGRLKE 720

  Fly   163 TSVKILDPNVCKRSYQY----ITKTMICAAALL--KDSCHGDSGGPLVSGGQ----LVGIVSYGI 217
            ..:.:::..||.| .:|    :..|.:||..|.  .|||.||||||||...:    |.|:.|:|:
Mouse   721 AQLPVIENKVCNR-VEYLNNRVKSTELCAGQLAGGVDSCQGDSGGPLVCFEKDKYILQGVTSWGL 784

  Fly   218 GCANPFFPGVYANVAELKPWI 238
            |||.|..||||..|:....||
Mouse   785 GCARPNKPGVYVRVSRFVDWI 805

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	76/257 (30%)
Plg	NP_032903.3	PAN_AP_HGF	<38..97	CDD:238532
		KR	101..183	CDD:214527
		KR	183..262	CDD:214527
		KR	273..354	CDD:214527
		KR	375..456	CDD:214527
		KR	480..562	CDD:214527	1/2 (50%)
		Tryp_SPc	582..807	CDD:238113	77/258 (30%)