Protein Alignment Ser12 and Klk1b4

DIOPT Version :10

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_035045.2
• Gene: Klk1b4 / 18048
• MGIID: 97320
• Length: 256
• Species: Mus musculus
• Alignment Length: 261
• Identity: 77/261 - (29%)
• Similarity: 115/261 - (44%)
• Gaps: 42/261 - (16%)

  Fly     5 WLVLVASVTLISAGSSPERIVGGHPVLISEV------PWQAALMYSEKYICGAVIYSDKIIITAA 63
            :|:|..:::|....::|       ||. |:|      ||..|:....||.||.|:.....::|||
Mouse     3 FLILFLALSLGGIDAAP-------PVQ-SQVDCENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAA 59

  Fly    64 HCVERPFDTLYSVRVGSVWKN------LGGQHARVAVIRKHEDYVSSTI----------LFNDIA 112
            ||    ::..|.|.:|   ||      ...||..|:....|.|:..|.:          ..||:.
Mouse    60 HC----YNDKYQVWLG---KNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLM 117

  Fly   113 VIRLVDTLIFNAEVRPIQLADSAPAAGTEASVSGWGE-IGILWLQPTSLLKTSVKILDPNVCKRS 176
            ::||.........|:||.|....|..|:....||||. ..|.:..|..|...::|:|....|.::
Mouse   118 LLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKA 182

  Fly   177 YQY-ITKTMICAAALLKDS--CHGDSGGPLVSGGQLVGIVSYG-IGCANPFFPGVYANVAELKPW 237
            ::. :|..|:||..:...|  |..||||||:..|.|.||.|:| ..|..|..|.||..:.:...|
Mouse   183 HEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSW 247

  Fly   238 I 238
            |
Mouse   248 I 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	71/241 (29%)
Klk1b4	NP_035045.2	Tryp_SPc	13..251	CDD:238113	74/251 (29%)
		Activation peptide homolog	18..24		3/13 (23%)