Protein Alignment Ser12 and Klk1

DIOPT Version :10

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_034769.4
• Gene: Klk1 / 16612
• MGIID: 102850
• Length: 261
• Species: Mus musculus
• Alignment Length: 260
• Identity: 81/260 - (31%)
• Similarity: 122/260 - (46%)
• Gaps: 31/260 - (11%)

  Fly     3 LHWLVLVASVTLISAGSSP---ERIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAH 64
            :.:|:|..:::|....::|   .|||||.....:..|||.|:....||.||.::.:...::||||
Mouse     1 MRFLILFLALSLGGIDAAPPVQSRIVGGFNCEKNSQPWQVAVYRFTKYQCGGILLNANWVLTAAH 65

  Fly    65 CVERPFDTLYSVRVGSVWKN------LGGQHARVAVIRKHEDYVSSTI----------LFNDIAV 113
            |    .:..|.|.:|   ||      ...||..|:....|.|:..|.:          ..||:.:
Mouse    66 C----HNDKYQVWLG---KNNFLEDEPSAQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLML 123

  Fly   114 IRLVDTLIFNAEVRPIQLADSAPAAGTEASVSGWGEI-GILWLQPTSLLKTSVKILDPNVCKRSY 177
            :||.........|:||.|....|..|:....||||.| .:.:..|..|...::|:|....|.:::
Mouse   124 LRLKKPADITDVVKPIDLPTEEPKLGSTCLASGWGSITPVKYEYPDELQCVNLKLLPNEDCAKAH 188

  Fly   178 -QYITKTMICAAAL--LKDSCHGDSGGPLVSGGQLVGIVSYGIG-CANPFFPGVYANVAELKPWI 238
             :.:|..|:||..:  .||:|.|||||||:..|.|.||.|:|.. |..|..||:|..|.....||
Mouse   189 IEKVTDDMLCAGDMDGGKDTCAGDSGGPLICDGVLQGITSWGPSPCGKPNVPGIYTRVLNFNTWI 253

  Fly   239  238
            Mouse   254  253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	75/235 (32%)
Klk1	NP_034769.4	Tryp_SPc	24..253	CDD:214473	75/235 (32%)