Protein Alignment Ser12 and KLK8

DIOPT Version :10

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 239
• Identity: 84/239 - (35%)
• Similarity: 123/239 - (51%)
• Gaps: 16/239 - (6%)

  Fly    16 SAGSS---PERIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAHCVERPFDTLYSVR 77
            :||.|   .::::|||.......||||||...::.:||.|:.....::||||| ::|   .|:||
Human    67 AAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHC-KKP---KYTVR 127

  Fly    78 VGS-VWKNLGGQHARVAVIRK--HEDYVSSTI--LFNDIAVIRLVDTLIFNAEVRPIQLADSAPA 137
            :|. ..:|..|....:.|::.  |..|.||.:  ..:|:.:::|.|.....::|:||.|||....
Human   128 LGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQ 192

  Fly   138 AGTEASVSGWGEIGILWLQ-PTSLLKTSVKILDPNVCKRSYQ-YITKTMICAAALL-KDSCHGDS 199
            .|.:.:|||||.:...... |.:|....|||.....|:.:|. .||..|:||.:.. .|:|.|||
Human   193 PGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGADTCQGDS 257

  Fly   200 GGPLVSGGQLVGIVSYGIG-CANPFFPGVYANVAELKPWILNAI 242
            |||||..|.|.||.|:|.. |.....||||.|:.....||...|
Human   258 GGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	78/223 (35%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	78/223 (35%)