Protein Alignment Ser12 and PRSS21

DIOPT Version :10

• Sequence 1: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 251
• Identity: 80/251 - (31%)
• Similarity: 119/251 - (47%)
• Gaps: 33/251 - (13%)

  Fly    23 RIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAHCVERPFD----TLYSVRVG---- 79
            |||||....:...|||.:|...:.::||..:.|.:..:|||||.|...|    :.:.|:.|
Human    41 RIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTS 105

  Fly    80 --SVWKNLGGQHARVAVIRKHEDYVSSTILFN---DIAVIRLVDTLIFNAEVRPIQLADSA--PA 137
              |.| :|...:.|..|   ...|:|...|.|   |||:::|...:.:...::||.|..|.  ..
Human   106 MPSFW-SLQAYYTRYFV---SNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFE 166

  Fly   138 AGTEASVSGWGEI--GILWLQPTSLLKTSVKILDPNVCKR---SYQY---ITKTMICA--AALLK 192
            ..|:..|:|||.|  ......|.:|.:..|.|::.::|..   .|.:   |...|:||  |...|
Human   167 NRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGGK 231

  Fly   193 DSCHGDSGGPLVSGGQ----LVGIVSYGIGCANPFFPGVYANVAELKPWILNAIEQ 244
            |:|.|||||||.....    .:|:||:|:||..|..||||.|::....||...:.|
Human   232 DACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMAQ 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	77/243 (32%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	78/244 (32%)