DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4267 and lipca

DIOPT Version :9

Sequence 1:	NP_001259919.1	Gene:	CG4267 / 33405	FlyBaseID:	FBgn0264979	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_957316.1	Gene:	lipca / 393997	ZFINID:	ZDB-GENE-040426-1361	Length:	514	Species:	Danio rerio

Alignment Length:	314	Identity:	88/314 - (28%)
Similarity:	129/314 - (41%)	Gaps:	62/314 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 CGRELFVGDVENLRNSGFDARHQTRIVIHGW-MSQSKGSHIRKVKNAYLSLTDPGPNGEPAPYED 147
            |..|||  ....|...||::.....|:|||| :.......|.::.:|..|...           :
Zfish    59 CALELF--QPHTLDACGFNSSLPLAIIIHGWSVDGMMEKWISRLASALKSSEG-----------N 110

  Fly   148 FNVIVCDWSKTSTNVNYYEVAKTVEDMGALLAELVRYLNQEANMHYDDVYVIGHSLGAQIAGSAG 212
            .||::.|| .|..:.:|...|:....:|..:|.|:.:|..........|::||:||||.|:|.||
Zfish   111 INVLIADW-LTLAHQHYPIAAQNTRIVGQDIAHLLSWLEDFKQFPLGKVHLIGYSLGAHISGFAG 174

  Fly   213 KQI-MPYR-FNTIYALDPAGPQFREKSDEYRIDASDASYVESIQT------SVSFGFEQPVGHAT 269
            ..: |..| ...|..||||||.|...|...|:...||.:|::|.|      .:|.|.:|||.|..
Zfish   175 SNLAMSGRTLGRITGLDPAGPMFEGMSHTDRLSPEDAKFVDAIHTFTLQRMGLSVGIKQPVAHFD 239

  Fly   270 FYPNYGKNQKKCYVY--------------------GCSHKRSHDYFIES-LTSPAGFWGPRCERH 313
            ||||.|..|..|.::                    .|:|:|:...||:| |.........:|..:
Zfish   240 FYPNGGSFQPGCQLHMQNIYAHLAQHGIMGFEQTVKCAHERAVHLFIDSLLNKDKQIMAYKCSDN 304

  Fly   314 ---DDGTWL---------LLMSDGEFRMGGEPSIPKNGTFYVKTYSKPPYAMGH 355
               |.|..|         |.....:.|.|      |:...::||.|..||.:.|
Zfish   305 TAFDKGNCLDCRKNRCNTLGYDIKKVRTG------KSKRLFLKTRSHMPYKLFH 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4267	NP_001259919.1	Lipase	64..351	CDD:278576	85/308 (28%)
CG4267	NP_001259919.1	Pancreat_lipase_like	71..347	CDD:238363	84/304 (28%)
lipca	NP_957316.1	lipo_lipase	44..488	CDD:132274	88/314 (28%)
		Pancreat_lipase_like	54..344	CDD:238363	84/304 (28%)
		PLAT_LPL	351..485	CDD:238856	1/2 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578582
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840