DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4267 and CG6675

DIOPT Version :9

Sequence 1:	NP_001259919.1	Gene:	CG4267 / 33405	FlyBaseID:	FBgn0264979	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_610132.3	Gene:	CG6675 / 35439	FlyBaseID:	FBgn0032973	Length:	390	Species:	Drosophila melanogaster

Alignment Length:	321	Identity:	166/321 - (51%)
Similarity:	211/321 - (65%)	Gaps:	16/321 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 TCNYTLVKKKTLG--VDPSFWKKFFKHLIPFTSSRGKMQFILFKRDFADCGRELFVGDVENLRNS 99
            ||:..|.:.:.:|  :|..|.||...:|.||.|.:.:|.|.||||:|.:||||:........|:.
  Fly    81 TCDKDLSESRGIGKFLDLPFIKKIASNLNPFGSKKLRMHFYLFKREFPECGREVDFSIERKWRHC 145

  Fly   100 GFDARHQTRIVIHGWMSQSKGSHIRKVKNAYLSLTDPGPNGEPAPYEDFNVIVCDWSKTSTNVNY 164
            ||:|...||::||||||||:||..|.||||||.      .||      :||||.|||.:|.|:||
  Fly   146 GFNASLPTRLMIHGWMSQSRGSFNRDVKNAYLK------KGE------YNVIVVDWSASSANINY 198

  Fly   165 YEVAKTVEDMGALLAELVRYLNQEANMHYDDVYVIGHSLGAQIAGSAGKQIMPYRFNTIYALDPA 229
            :.|.|.:|..||.||:.:|.||::....:|.:|:|||||||||||||||::.|.:.|||:|||||
  Fly   199 FSVVKLIETFGAELAQFIRNLNRQFGADFDSMYLIGHSLGAQIAGSAGKRLKPVKVNTIFALDPA 263

  Fly   230 GPQFREKSDEYRIDASDASYVESIQTSVSFGFEQPVGHATFYPNYGKNQKKCYVYGCSHKRSHDY 294
            ||:||.:..|:|||.|||.||||:.||.:|||.:|.|.||||||||..|..||..||||.||:..
  Fly   264 GPKFRHRGTEFRIDPSDAKYVESMHTSANFGFRRPTGSATFYPNYGAYQHSCYYLGCSHIRSYQM 328

  Fly   295 FIESLTSPAGFWGPRCERHDDGTWLLLMSDGE-FRMGGEPSIPKNGTFYVKTYSKPPYAMG 354
            |.||:.||.||||..|.| |:|.|....|..: .:|.|||||.|.|.|||||.|..|:|:|
  Fly   329 FAESINSPLGFWGTPCIR-DNGRWQCDYSQRQSIQMAGEPSIHKEGIFYVKTSSSDPFALG 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4267	NP_001259919.1	Lipase	64..351	CDD:278576	154/287 (54%)
CG4267	NP_001259919.1	Pancreat_lipase_like	71..347	CDD:238363	150/276 (54%)
CG6675	NP_610132.3	Pancreat_lipase_like	116..381	CDD:238363	150/277 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438406
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000679
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840