Protein Alignment CG4267 and LIPH

DIOPT Version :9

• Sequence 1: NP_001259919.1
• Gene: CG4267 / 33405
• FlyBaseID: FBgn0264979
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_640341.1
• Gene: LIPH / 200879
• HGNCID: 18483
• Length: 451
• Species: Homo sapiens
• Alignment Length: 418
• Identity: 98/418 - (23%)
• Similarity: 160/418 - (38%)
• Gaps: 126/418 - (30%)

  Fly    18 FAAIVFASSSEKTELDPNATCNYTLVKKKTLGVDPSFWKKFFKHLIPFTSSRGKMQFILFKRDFA 82
            |.:::..|.|:..|     ||             |||.:..|...:..|..  .::.:|:.|...
Human     7 FISLLCLSRSDAEE-----TC-------------PSFTRLSFHSAVVGTGL--NVRLMLYTRKNL 51

  Fly    83 DCGRELFVGDVENLRNSGF---DARHQTRIVIHGWMSQSKGSHIRKVKNAYLSLTDPGPNGEPAP 144
            .|        .:.:.:|.|   :...:|..::||:.                      |.|.|..
Human    52 TC--------AQTINSSAFGNLNVTKKTTFIVHGFR----------------------PTGSPPV 86

  Fly   145 Y-----------EDFNVIVCDWSKTSTNVNYYEVAKTVEDMGALLAELV-RYLNQEANMHYDDVY 197
            :           ||.||:|.||::.:|.:.|...:.....:..:|.|.: :.|.:.|::  ||:|
Human    87 WMDDLVKGLLSVEDMNVVVVDWNRGATTLIYTHASSKTRKVAMVLKEFIDQMLAEGASL--DDIY 149

  Fly   198 VIGHSLGAQIAGSAGKQIMPYRFNTIYALDPAGPQFREKSDEYRIDASDASYVESIQTSV-SFGF 261
            :||.||||.|:|..|:....: ...|..||||||.|..|..:.|:|.|||.:|:.|.:.. :.|:
Human   150 MIGVSLGAHISGFVGEMYDGW-LGRITGLDPAGPLFNGKPHQDRLDPSDAQFVDVIHSDTDALGY 213

  Fly   262 EQPVGHATFYPNYGKNQKKC--------YVYGCSHKRSHDYFIESLTSPAGFWGPRCERHDD--- 315
            ::|:|:..||||.|.:|..|        ..:.|.|:||...::.||..........|:.:.|
Human   214 KEPLGNIDFYPNGGLDQPGCPKTILGGFQYFKCDHQRSVYLYLSSLRESCTITAYPCDSYQDYRN 278

  Fly   316 ------GT---------------WLLLMSDGEFRMGGEPSIPKNGTFYVKTYSKPPYAMGH---- 355
                  ||               |      .:...|.:|.:.|   .:..|..:.|:.|.|
Human   279 GKCVSCGTSQKESCPLLGYYADNW------KDHLRGKDPPMTK---AFFDTAEESPFCMYHYFVD 334

  Fly   356 --RWQTEPPPREDDIE--------NSTE 373
              .|...  .|..||.        |:||
Human   335 IITWNKN--VRRGDITIKLRDKAGNTTE 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4267	NP_001259919.1	Lipase	64..351	CDD:278576	78/334 (23%)
		Pancreat_lipase_like	71..347	CDD:238363	77/323 (24%)
LIPH	NP_640341.1	Pancreat_lipase_like	39..303	CDD:238363	73/304 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145273
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840