Protein Alignment sau and VPS74

DIOPT Version :10

• Sequence 1: NP_608658.1
• Gene: sau / 33402
• FlyBaseID: FBgn0267378
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_010660.1
• Gene: VPS74 / 851978
• SGDID: S000002780
• Length: 345
• Species: Saccharomyces cerevisiae
• Alignment Length: 344
• Identity: 129/344 - (37%)
• Similarity: 187/344 - (54%)
• Gaps: 63/344 - (18%)

  Fly     7 LVRRSVKPRENGGAEGGLNANTPDDNQDALDNLKDQEDNIDDG-------DSKETR--------- 55
            |.||.|. |.:.|....::::..:...|.:.|:....|: |:|       |.:|::
Yeast     4 LQRRRVN-RADSGDTSSIHSSANNTKGDKIANIAVDGDD-DNGTNKKIAYDPEESKLRDNINIPT 66

  Fly    56 LTLMEEVLLLGLKDKEGYTSFWNDCISSGLRGCILIELGLRGRV-MIEKSGMRRRGLCTRKLILK 119
            |||||||||:||:|:|||.|||||.||..|||||:|||.|||:: :::.|..:|..|..|.:.:.
Yeast    67 LTLMEEVLLMGLRDREGYLSFWNDSISYALRGCIIIELALRGKIRILDDSARKRFDLSERLIEVI 131

  Fly   120 SDQQTGDVLLDEALKHIKETDPPETVQSWIEYLSGETWNPLKLRYQLKNVRERLAKNLVEKGVLT 184
            ...:||:|||||.|:.:| .|.|.::.:||:.|||||||.||:.||||.|||||||.||:||||.
Yeast   132 DSSKTGEVLLDETLQLMK-NDEPLSISNWIDLLSGETWNLLKINYQLKQVRERLAKGLVDKGVLR 195

  Fly   185 TEKQNFLLFDMTTHPLSDNVVKCRLVKKIQDSVLSKWVNDPQRMDK-------------RMLALI 236
            ||.:||.||||.|||::|  ..|:  :.|:..|||..|:....:..             |.||||
Yeast   196 TEMKNFFLFDMATHPIAD--ASCK--EAIKRRVLSVLVSRNMELSYNEYFPETTSFKIIRTLALI 256

  Fly   237 FLAHASDVIENAFAPLNDDDYEVAMKRVRELL--------DLDFEAE-SAKPNAN---------- 282
            ..::.::|:||....|..:..:.|:.|..|::        ||:.|.| ....|.|
Yeast   257 CGSYGANVLENVLTTLEYEKRDKAISRAEEIMAQFSQYPFDLEKETELGVSVNLNKEVKEEIENN 321

  Fly   283 -------EILWAVFMAFTK 294
                   |::..||..|::
Yeast   322 PGHDLQLEVIAGVFEVFSR 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sau	NP_608658.1	GPP34	58..269	CDD:428605	104/232 (45%)
VPS74	NP_010660.1	GPP34	69..289	CDD:428605	104/224 (46%)