Protein Alignment papi and tdrd5

DIOPT Version :10

• Sequence 1: NP_608657.1
• Gene: papi / 33401
• FlyBaseID: FBgn0031401
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: XP_031756124.1
• Gene: tdrd5 / 780220
• XenbaseID: XB-GENE-5884032
• Length: 1010
• Species: Xenopus tropicalis
• Alignment Length: 544
• Identity: 119/544 - (21%)
• Similarity: 208/544 - (38%)
• Gaps: 138/544 - (25%)

  Fly     9 ATPTYKLLLGFGLC--SLGGAMLYAYFKTRNDEEEAD-SGGQRPASGIRGQTEEQKPQKEVCLKI 70
            |.|::..:|...|.  |:....|:..........||| |....|.:.:. :..|:|.:||  ||:
 Frog   353 AVPSHNSVLSNSLVGNSVSSETLFTKMSRPTSHVEADHSAASEPDASVL-EWLEKKLEKE--LKL 414

  Fly    71 VVDNEHVPLIMGRGGSNIKLIEEKTLAKIR--LRDKDSGHKFCDISGVPDAVKA--ARALLIKEI 131
            .:..:      |.|||    :.:.....|:  :.....|.|   ||.:|...|:  .:.|..||:
 Frog   415 CLARK------GAGGS----VSDALRMDIQHVVNQHSDGLK---ISQLPTVFKSFTGKDLPFKEL 466

  Fly   132 ERAPVVKVELQVPQRLASKINGRGGELLQEIRSSSLAKLNIDLNGRNGKAKITIIGNQKQVNIAR 196
            ....|:            ::.|..|::|       ..:..:|     ||       :.|..:..:
 Frog   467 GFISVM------------ELVGSLGDIL-------CVESTVD-----GK-------DWKLFDAKK 500

  Fly   197 KMLDDQ----IEEDEELVRSMEEVEQRREPRRSPTNSIASSMYSS------QTSLSSHTQ---PR 248
            |.|.|:    :.....::.|....:|...|.: |..:|.|.:...      :..|.|..|   |.
 Frog   501 KDLVDEFSAGLPSTSSILSSWNSSQQTTTPVK-PVGTIFSKVDEKLWWGPLELKLCSTEQIDIPP 564

  Fly   249 DKL-------MASKGEGKPMEVYVSAVASPTKFWVQLIGPQ-SKKLDSMVQEMTSYYSSAENRAK 305
            |.:       :.|...|..:.|||..:.||::|:|:..|.. |:||:.|:.||...||:.....:
 Frog   565 DAVRNQKLHCLPSMKRGFMIGVYVENIESPSQFYVRCCGKDTSEKLEDMMIEMRHCYSNECVSER 629

  Fly   306 HVLT--APYVGQIVAAVFKFDEKWYRAEIVDIMPNQYNPKEQVIDLYFVDYGDSEYISPADICEL 368
            :::|  ...||||.|.....|..|||..:.||      ...:::|:::.|:|:...:..:.:..|
 Frog   630 YIVTDNCISVGQIYALRVPGDVWWYRVIVHDI------KNSELLDVFYPDFGNVATVKKSWLRFL 688

  Fly   369 RTDFLTLRFQAVECFLANVKSTIQTEPITWPKSSIAKFEELTEVAHWRKLIARVVTYKERPRATT 433
            :..::.:..|||...|..|.||..    .|...:|.||::|....   .|:..|:.|.:
 Frog   689 KNCYMKIPAQAVPSSLPYVTSTED----QWSAQAIKKFQQLCSCI---PLVGMVLQYVQ------ 740

  Fly   434 AVSAAAKEGTPLPGVELFDPADNSELNIADLMITQGFA--------------------------- 471
                      .:..:.|.|.:...:|.:..|:|:||.|
 Frog   741 ----------DILHIFLCDTSSEEDLYLHQLLISQGLAKMEPEHACKKISKKRNPFMQYLTPSQE 795

  Fly   472 LPLDDSYPVRSRSSTPSSNSDSTI 495
            .|.::|    |:.|.||.:|.|.|
 Frog   796 QPQEES----SQLSVPSESSQSEI 815

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
papi	NP_608657.1	KH_1	68..129	CDD:459630	14/64 (22%)
		KH-I	140..209	CDD:469614	10/72 (14%)
		Tudor_TDRD2	281..383	CDD:410483	27/104 (26%)
tdrd5	XP_031756124.1	LOTUS_1_TDRD5	50..142	CDD:193599
		LOTUS_2_TDRD5	174..242	CDD:193589
		LOTUS_3_TDRD5	426..499	CDD:193590	18/106 (17%)
		Tudor_TDRD5	587..704	CDD:410490	34/122 (28%)