DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment papi and tud

DIOPT Version :9

Sequence 1:NP_608657.1 Gene:papi / 33401 FlyBaseID:FBgn0031401 Length:576 Species:Drosophila melanogaster
Sequence 2:NP_476773.1 Gene:tud / 37417 FlyBaseID:FBgn0003891 Length:2515 Species:Drosophila melanogaster


Alignment Length:320 Identity:67/320 - (20%)
Similarity:133/320 - (41%) Gaps:67/320 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   263 VYVSAVASPTKFWVQLIGPQSKKLDSMVQEMTSYYSSAENRA--KHVLTAPYVGQIVAAVFKFDE 325
            |.:..:.||:.|:||.:. ...|.:.::.||.||| :|..|.  :.:|.||       .:.|.|:
  Fly   599 VEIRFIDSPSNFYVQKVA-NIGKFEQLMDEMFSYY-NANQRVPDQLILGAP-------CIVKCDQ 654

  Fly   326 KWYRAEIVDIMPNQYNPKEQVIDLYFVDYGDSEYISPADICELRTDFLTLRFQAVECFLANVK-S 389
            :||||||:.:        :..:.:..||:|..:.:....|..:....|.:..||::|.|...: |
  Fly   655 EWYRAEILRV--------DDSVIVRHVDFGYEQNVKRHLIGHIAEKHLEMPRQAIKCCLKGFENS 711

  Fly   390 TIQTEPITWPKSSIAKFEELTEVAHWRKLIARVVTYKERPRATTAVSAAAKEGTPLPGVELFDPA 454
            .:..:.||      .:||.|.|.::.|:....|..::..|.....|:..||              
  Fly   712 ELSEDKIT------DQFEMLAEESNIRRRTFSVRIFRIEPDGLNVVNLLAK-------------- 756

  Fly   455 DNSELNIADLMITQGFALPLDDSYPVRSRSSTPSSNSDSTIEELCVSNPVTPLTPHSPMSMSIDV 519
               .||:...:..  .::|.:....:..    ...|:::|..|..:|:.:.       .|..::.
  Fly   757 ---NLNVMKKLYK--LSMPFEQYLSLEK----GQFNANNTRAESVISSELN-------KSHILNS 805

  Fly   520 DSITQAENEHLAQQLQHLQHKLNGND----------IKNINPAKLTATDLENGNNNNAST 569
            .||.:.||....|:.:..|.|::...          :|:::.:| .:||.:..::.:|.:
  Fly   806 TSIGETENRLQEQEKEQQQKKVDVRQQQLAVEIPQAVKSVSGSK-NSTDWDKRSSTSAGS 864

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
papiNP_608657.1 KH-I 68..127 CDD:238053
KH_1 138..201 CDD:306517
TUDOR 257..386 CDD:306940 34/124 (27%)
tudNP_476773.1 DUF1421 198..>397 CDD:284607
TUDOR 406..524 CDD:278965
TUDOR 454..510 CDD:197660
TUDOR 591..707 CDD:278965 34/124 (27%)
TUDOR 644..693 CDD:197660 15/63 (24%)
TUDOR 1012..1132 CDD:278965
TUDOR 1062..1119 CDD:197660
TUDOR 1309..1425 CDD:278965
TUDOR 1354..1411 CDD:197660
TUDOR 1614..1727 CDD:278965
TUDOR 1666..1711 CDD:119391
TUDOR 1791..1906 CDD:278965
TUDOR 1843..1886 CDD:119391
TUDOR 1975..2089 CDD:278965
TUDOR 2028..2069 CDD:119391
TUDOR 2159..2277 CDD:278965
TUDOR 2210..2264 CDD:197660
TUDOR 2345..2458 CDD:278965
TUDOR 2396..2437 CDD:119391
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45452777
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR22948
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.030

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