Protein Alignment Uch and UCHL3

DIOPT Version :9

• Sequence 1: NP_001188681.1
• Gene: Uch / 33397
• FlyBaseID: FBgn0010288
• Length: 227
• Species: Drosophila melanogaster
• Sequence 2: XP_011533514.1
• Gene: UCHL3 / 7347
• HGNCID: 12515
• Length: 294
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 115/289 - (39%)
• Similarity: 157/289 - (54%)
• Gaps: 67/289 - (23%)

  Fly     4 WTPLESNPEVLTKYIHKLGVSPAWSVTDVIGLEDDTLEWIPRPVKAFILLFPCSETYEKHRAEEH 68
            |.|||:||||..:::.:||:.|.|...||.|::.:.|..:||||.|.:||||.:|.||..|.||.
Human     6 WLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEEE 70

  Fly    69 DRIKEVEEQHPEDLFYMRQFTHNACGTVALIHSVANNKE-VDIDRG-VLKDFLEKTASLSPEERG 131
            ::||...:.....:::|:|...|||||:.|||::||||: :..:.| .||.|||::.|:|||||.
Human    71 EKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERA 135

  Fly   132 RALEKDEKFTADHEALAQEGQTNAA------------------------------NH-------- 158
            |.||..:.....||..|.||||.::                              ||
Human   136 RYLENYDAIRVTHETSAHEGQTESSSPSSSQPHSSHCRTKASSLCHHASLPWVKRNHVGPAKATS 200

  Fly   159 ---------------------------EKVIHHFIALVNKEGTLYELDGRKSFPIKHGPTSEETF 196
                                       |||..||||||:.:|.||||||||.|||.||.||:||.
Human   201 PSLRLRRWRPFLRLPSLGLHSVAPSIDEKVDLHFIALVHVDGHLYELDGRKPFPINHGETSDETL 265

  Fly   197 VKDAAKVCKEFMARDPNEVRFTVLALTAA 225
            ::||.:|||:||.|||:|:||..:||:||
Human   266 LEDAIEVCKKFMERDPDELRFNAIALSAA 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uch	NP_001188681.1	Peptidase_C12_UCH_L1_L3	4..222	CDD:187737	111/284 (39%)
UCHL3	XP_011533514.1	Peptidase_C12_UCH_L1_L3	6..291	CDD:187737	111/284 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	208	1.000	Domainoid score	I2863
eggNOG	1	0.900	-	-		E1_KOG1415
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4377
Inparanoid	1	1.050	229	1.000	Inparanoid score	I3458
Isobase	1	0.950	-	0	Normalized mean entropy	S1557
OMA	1	1.010	-	-		QHG53971
OrthoDB	1	1.010	-	-		D1013351at2759
OrthoFinder	1	1.000	-	-		FOG0001664
OrthoInspector	1	1.000	-	-		otm41612
orthoMCL	1	0.900	-	-		OOG6_101218
Panther	1	1.100	-	-	LDO	PTHR10589
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1588
SonicParanoid	1	1.000	-	-		X1061
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.820