Protein Alignment Uch and Uchl1

DIOPT Version :10

• Sequence 1: NP_476940.1
• Gene: Uch / 33397
• FlyBaseID: FBgn0010288
• Length: 227
• Species: Drosophila melanogaster
• Sequence 2: NP_035800.2
• Gene: Uchl1 / 22223
• MGIID: 103149
• Length: 223
• Species: Mus musculus
• Alignment Length: 222
• Identity: 102/222 - (45%)
• Similarity: 150/222 - (67%)
• Gaps: 6/222 - (2%)

  Fly     6 PLESNPEVLTKYIHKLGVSPAWSVTDVIGLEDDTLEWIPRPVKAFILLFPCSETYEKHRAEEHDR 70
            |:|.|||:|.|.:.||||:..|...||:|||::||..:|.|..|.:||||.:..:|..|.::.:.
Mouse     5 PMEINPEMLNKVLAKLGVAGQWRFADVLGLEEETLGSVPSPACALLLLFPLTAQHENFRKKQIEE 69

  Fly    71 IKEVEEQHPEDLFYMRQFTHNACGTVALIHSVANNKE-VDIDRG-VLKDFLEKTASLSPEERGRA 133
            :|. :|..|: :::|:|...|:|||:.|||:||||:: ::.:.| |||.||.:|..||||:|.:.
Mouse    70 LKG-QEVSPK-VYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEKLSPEDRAKC 132

  Fly   134 LEKDEKFTADHEALAQEGQTNAANHEKVIHHFIALVNKEGTLYELDGRKSFPIKHGPTSEETFVK 198
            .||:|...|.|:::|||||...  .:||..|||...|.:|.|||||||..||:.||.:||::.::
Mouse   133 FEKNEAIQAAHDSVAQEGQCRV--DDKVNFHFILFNNVDGHLYELDGRMPFPVNHGASSEDSLLQ 195

  Fly   199 DAAKVCKEFMARDPNEVRFTVLALTAA 225
            ||||||:||..|:..||||:.:||..|
Mouse   196 DAAKVCREFTEREQGEVRFSAVALCKA 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uch	NP_476940.1	Peptidase_C12_UCH_L1_L3	4..222	CDD:187737	99/217 (46%)
Uchl1	NP_035800.2	Peptidase_C12_UCH_L1_L3	5..219	CDD:187737	99/217 (46%)
		Interaction with ubiquitin. /evidence=ECO:0000250|UniProtKB:P09936	5..10		2/4 (50%)
		Interaction with ubiquitin. /evidence=ECO:0000250|UniProtKB:P09936	211..216		4/4 (100%)