Protein Alignment CG15385 and PXYLP1

DIOPT Version :10

• Sequence 1: NP_608654.1
• Gene: CG15385 / 33396
• FlyBaseID: FBgn0031397
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_689495.1
• Gene: PXYLP1 / 92370
• HGNCID: 26303
• Length: 480
• Species: Homo sapiens
• Alignment Length: 587
• Identity: 142/587 - (24%)
• Similarity: 229/587 - (39%)
• Gaps: 152/587 - (25%)

  Fly    16 AFYCYVLLSVWIFLLIAGMYRYMGNVESTPSGGSVFGPSSSGTVSSLGGD-------SSPSSTAQ 73
            |...:|.||:..|.||.         .|||..|     .||.:...:..|       :.|...|.
Human    15 ALLAFVSLSLQFFHLIP---------VSTPKNG-----MSSKSRKRIMPDPVTEPPVTDPVYEAL 65

  Fly    74 RFAKYRERCAPLAQLQRLDDGGILEGWKLQGVLLVIRHGDRGP---ISHVRSAGINCGVSGGSDN 135
            .:      |...:..:|..:|.....:||..|.:.||||||.|   |...:...|:|.:......
Human    66 LY------CNIPSVAERSMEGHAPHHFKLVSVHVFIRHGDRYPLYVIPKTKRPEIDCTLVANRKP 124

  Fly   136 LVNRYRSFLYNSSSSASGSNHMYWNKVGPFHGFPLLPATERGCPLGQLTYKGISQLLHVGDIMHQ 200
            ...:..:|:.:.|..:..|..      .|.:..||.| ....|.:|:||..|:.|.|..|.::..
Human   125 YHPKLEAFISHMSKGSGASFE------SPLNSLPLYP-NHPLCEMGELTQTGVVQHLQNGQLLRD 182

  Fly   201 VYAHPLGLLLKPNPNRASVETTPHTLLNSDEVVVFTTRYRRTFQSALAMLFTLLPADKWLALNVR 265
            :|.....||    ||..|          :|::.:.||...||.||.||:|:..||...|..:..|
Human   183 IYLKKHKLL----PNDWS----------ADQLYLETTGKSRTLQSGLALLYGFLPDFDWKKIYFR 233

  Fly   266 ESHSMAFCFGECSCP------QSALLRKRLEAMGDKQLLKR-GDVLDVMQWIGGTILQHTPN--- 320
            ...|..||.|.|.||      :....|:.|..:.:.||.|. |::..::.         .|.
Human   234 HQPSALFCSGSCYCPVRNQYLEKEQRRQYLLRLKNSQLEKTYGEMAKIVD---------VPTKQL 289

  Fly   321 GISNPFEVVDALLTVLCHDATLPCRRKKALSTPKPLRKNSNQELVDVINIDQDETAANLMQEAQT 385
            ..:||   :|::|...||:.:.||.|
Human   290 RAANP---IDSMLCHFCHNVSFPCTR--------------------------------------- 312

  Fly   386 QVEPDSPEVENGNPSVQADEAQEGCVEPSHVDTLMS--FADELSQRSAGHSYYKLSGLLRSYGMI 448
                                  .|||:..|...:.:  ..||..:|.. ..|:..| ||.::.::
Human   313 ----------------------NGCVDMEHFKVIKTHQIEDERERREK-KLYFGYS-LLGAHPIL 353

  Fly   449 RHIVSYMLKMISGDRTK-FVLYSGHDCTMQYLTAALGIITNQGQTIAYASRLAFEVYRS-DAHTD 511
            ...:..|.:...|.:.: |.|||.||.|:..:.:|||:  ::.:...:|:||.||:::. :..::
Human   354 NQTIGRMQRATEGRKEELFALYSAHDVTLSPVLSALGL--SEARFPRFAARLIFELWQDREKPSE 416

  Fly   512 YYFRVVYNGKDVTQQIDFCEGGKSLRVTRDSRGNKADLCPIENIIRFLHEDYFSPL--NATNFKE 574
            :..|::|||.|||....||:       ....|..| .:||:||::||:..|.|..|  :.||:.:
Human   417 HSVRILYNGVDVTFHTSFCQ-------DHHKRSPK-PMCPLENLVRFVKRDMFVALGGSGTNYYD 473

  Fly   575 AC 576
            ||
Human   474 AC 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15385	NP_608654.1	HP	101..519	CDD:472174	100/434 (23%)
PXYLP1	NP_689495.1	HP	87..424	CDD:472174	100/434 (23%)