DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31668 and slc5a6b

DIOPT Version :9

Sequence 1:	NP_001097055.2	Gene:	CG31668 / 33395	FlyBaseID:	FBgn0051668	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	XP_005158632.1	Gene:	slc5a6b / 796312	ZFINID:	ZDB-GENE-050913-86	Length:	603	Species:	Danio rerio

Alignment Length:	608	Identity:	198/608 - (32%)
Similarity:	323/608 - (53%)	Gaps:	60/608 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 FGTVDYAVFLGVTILSIAIGLYFGFIRKSRNGPKTTTPTNEAPERRHQNFGSKKMNDYMMGSRNL 70
            |..:||.:|..:.:.|::||||:.|    ..|.::||                  .::::..|::
Zfish     9 FTVIDYVIFGLLLVASMSIGLYYAF----TGGRQSTT------------------QEFLIADRSM 51

  Fly    71 RVFPVGMSLIASCISAVAIIGTPSEIYNYGTQYCFIVIALVLQGLAVSYIYLPVFSALQVTSSYE 135
            :..|:.:||:|:..|||||||||:|:|.:||||.||..:.||..|..::|::|:|..|.:||.|:
Zfish    52 KCLPLSLSLMATFQSAVAIIGTPAEVYAHGTQYWFIGCSYVLGLLIPAHIFIPLFYRLHLTSVYQ 116

  Fly   136 YLEMRFHSAIRSIVSIIFILDVVLYLPFLAYLPALALNQVSGMNMYLIEAFIIVICVIYTVLGGL 200
            |||:||..|:|...::.||..:|:|:....|.||||||.|:|.:::.......::|.:||.||||
Zfish   117 YLELRFCKAVRICGTVTFIFQMVIYMGVGIYTPALALNAVTGFHLWGAVLATGLVCTLYTALGGL 181

  Fly   201 KAVVHTDIWQVVIMFASVLTIVVLATCYIDDQADFLE---GLVR-GGRLIFSETNPSPFARHTVW 261
            ||||.||::|.|:||...|.::::..    .||..|.   |.|| |||:...:.||.|..|||.|
Zfish   182 KAVVWTDVFQTVVMFTGQLAVIIVGV----HQAGGLSEAWGKVRDGGRISGIDLNPDPTVRHTFW 242

  Fly   262 SVVIGNTFYWTSLNAVHQTVVHRYMSLPTLKMARASIAFLVVGAAFFISLLCYLGLLIFHAYRDC 326
            ::.:|..|...||..|:|..|.||:|..|.:.|..|...:.......:.|.|.:||::|..|...
Zfish   243 TLAVGGVFLMLSLYGVNQAQVQRYLSSRTEREAVMSCYMVFPCLQLALLLSCLMGLVMFACYGQN 307

  Fly   327 DPLSAGLIMNDDQLVPLFVVNSLGHVYGMPGLFIAGIFGASLSSLSVYLNSTSLVILQDLVRGCF 391
            .|:....|.:.||:|..||::.|.:..|:||||:|.:|.||||::|...||.:.|.:.||::..:
Zfish   308 SPVEQQYITSKDQMVLYFVMDMLQNFPGLPGLFVACLFSASLSTISSAFNSLATVTMVDLIKPHY 372

  Fly   392 KMELGEWASTIVVKGSIVVLGLLAFAMVFVLEKV-SGVLSISVSLAAIAASSTFGIFTVGMLVPW 455
            .|.  |..:|::.|...:..|::..||.:::..: |.||..::|:..:......|:|.:|:..|.
Zfish   373 SMT--EARATLLSKLLALSYGIICLAMAYLVHLMNSSVLQAALSIFGMIGGPLLGLFCLGIFFPC 435

  Fly   456 ANTVGTAVGGIASVLLTGWISFGSQFAAASGQLGSQRLPVSVEGCLANASVAENAWVAEEE---- 516
            ||::|...|..|.:|:..|:..|....    ::.|..:|: :...:....|:||...|..|
Zfish   436 ANSIGAVTGLSAGLLMAFWVGIGGFLT----RMPSPVIPL-LNSTITVPDVSENITAATAELEAD 495

  Fly   517 -----VFPLYRLSYHWISPIGVLTVVVVGSLVSLVTKPTDIKSLDSDLITPVI---HRFL-PKEC 572
                 :...|.|||.|.|.:...||::||.::|.:|.||....:.|..:.||:   ..:| |..|
Zfish   496 SRSAGLHGFYSLSYMWYSALSSCTVLIVGLIISCITGPTKGDDVASGTVYPVVKTAQSYLKPSTC 560

  Fly   573 FE--------QGNAEEN-SVKDN 586
            .:        .|..|.| :||::
Zfish   561 CKTTAEHKQVDGQKEMNGTVKED 583

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31668	NP_001097055.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	178/535 (33%)
slc5a6b	XP_005158632.1	SLC5-6-like_sbd	9..532	CDD:294310	184/555 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820