Protein Alignment CG31668 and SLC5A5

DIOPT Version :10

• Sequence 1: NP_001097055.2
• Gene: CG31668 / 33395
• FlyBaseID: FBgn0051668
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_011526494.1
• Gene: SLC5A5 / 6528
• HGNCID: 11040
• Length: 654
• Species: Homo sapiens
• Alignment Length: 621
• Identity: 191/621 - (30%)
• Similarity: 302/621 - (48%)
• Gaps: 74/621 - (11%)

  Fly     6 FGTVDYAVFLGVTILSIAIGLYFGFIRKSRNGPKTTTPTNEAPERRHQNFGSKKMNDYMMGSRNL 70
            ||..||.||..:.::|..|||:.|..|.                      |.:...|:..|.|.|
Human    12 FGAWDYGVFALMLLVSTGIGLWVGLARG----------------------GQRSAEDFFTGGRRL 54

  Fly    71 RVFPVGMSLIASCISAVAIIGTPSEIYNYGTQYCFIVIALVLQGLAVSYIYLPVFSALQVTSSYE 135
            ...|||:||.||.:|||.::|.|||.|.||.::.::.:..:|..:..:.:::|||..|.:||:||
Human    55 AALPVGLSLSASFMSAVQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYE 119

  Fly   136 YLEMRFHSAIRSIVSIIFILDVVLYLPFLAYLPALALNQVSGMNMYLIEAFIIVICVIYTVLGGL 200
            ||||||..|:|...::.:|:..:||...:.|.|||.||||:|::::.......:||..||.:||:
Human   120 YLEMRFSRAVRLCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGM 184

  Fly   201 KAVVHTDIWQVVIMFASVLTIVVLATCYIDDQADFLEGLVRGGRLIFSETNPSPFARHTVWSVVI 265
            ||||.||::|||:|.:....::......:......|.......|:...:.||.|.:|:|.|:.|:
Human   185 KAVVWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFWTFVV 249

  Fly   266 GNTFYWTSLNAVHQTVVHRYMSLPTLKMARASIAFLVVGAAFFISLLCYLGLLIFHAYRDCDPLS 330
            |.|..|.|:..|:|..|.||::..|.|.|:.::....||....:|.....|:::|..|.|||||.
Human   250 GGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGIVMFVFYTDCDPLL 314

  Fly   331 AGLIMNDDQL-----------VPLFVVNSLGHVYGMPGLFIAGIFGASLSSLSVYLNSTSLVILQ 384
            .|.|...|||           :||.|::....:.|:||||:|..:..:||:.|..:|:.:.|.::
Human   315 LGRISAPDQLSGRLTPSSPQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVE 379

  Fly   385 DLVRGCFKMELGEWASTIVVKGSIVVLGLLAFAMVFVLEKV--SGVLSISVSLAAIAASSTFGIF 447
            ||::...: .|......|:.||..::.| .|...|..|..:  .|||..|.::..:.:....|.|
Human   380 DLIKPRLR-SLAPRKLVIISKGLSLIYG-SACLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAF 442

  Fly   448 TVGMLVPWANTVGTAVGGIASVLLTGWISFGSQFAAASGQLGSQRLPVSVEGCLA---NASVAEN 509
            .:||.:|..||.|...|..|.:.|:.|::.|:.....|.|. .:.||.|...|:|   |||
Human   443 ILGMFLPACNTPGVLAGLGAGLALSLWVALGATLYPPSEQT-MRVLPSSAARCVALSVNAS---- 502

  Fly   510 AWVAEEEVFP----------------------LYRLSYHWISPIGVLTVVVVGSLVSLVTKPTDI 552
             .:.:..:.|                      .|.:||.:...:|.||.|:.|:|:|.:|.||..
Human   503 -GLLDPALLPANDSSRAPSSGMDASRPALADSFYAISYLYYGALGTLTTVLCGALISCLTGPTKR 566

  Fly   553 KSLDSDLITPVIHR----FLPKECFEQGNAEENSVK 584
            .:|...|:...:.|    ..|||  |....::|.||
Human   567 STLAPGLLWWDLARQTASVAPKE--EVAILDDNLVK 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31668	NP_001097055.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	169/559 (30%)
SLC5A5	XP_011526494.1	SLC5sbd_NIS	15..565	CDD:271393	178/579 (31%)