Protein Alignment CG31668 and SLC5A4

DIOPT Version :9

• Sequence 1: NP_001097055.2
• Gene: CG31668 / 33395
• FlyBaseID: FBgn0051668
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_016884409.1
• Gene: SLC5A4 / 6527
• HGNCID: 11039
• Length: 689
• Species: Homo sapiens
• Alignment Length: 611
• Identity: 136/611 - (22%)
• Similarity: 242/611 - (39%)
• Gaps: 120/611 - (19%)

  Fly    36 NGPKTTTPT--NEAPERRHQNFGSKK-----------MNDYMMGSRNLRVFPVGMSLIASCISA- 86
            :|.|.:.|.  :|.|.:||....|..           :..:.:..|::..:|:|.||.||.|.:
Human    48 SGSKLSVPVLLSETPTKRHGPLASHNHSAMLKTNRGTIGGFFLAGRDMAWWPMGASLFASNIGSN 112

  Fly    87 --VAIIGT--PSEIYNYGTQYCFIVIALVLQGLAVSYIYLPVFSALQVTSSYEYLEMRFH----S 143
              |.:.||  .|.:.....::...|:.|:|     .:|::|::....|.:..|||:.||.    .
Human   113 HYVGLAGTGAASGVATVTFEWTSSVMLLIL-----GWIFVPIYIKSGVMTMPEYLKKRFGGERLQ 172

  Fly   144 AIRSIVSIIFILDVVLYLPFLAYLPALALNQVSGMNMYLIEAFIIVICVIYTVLGGLKAVVHTDI 208
            ...||:| :||. |||.:....:..|:.:....|:::||....::.:..:||..|||.:|::||.
Human   173 VYLSILS-LFIC-VVLLISADIFAGAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIYTDT 235

  Fly   209 WQVVIMFASVLTIVVLATCYIDDQADFLE-------GLVRGGRLIFSETNPSPFAR--HTVWSVV 264
            .|.:||......::..|...:.....|.|       .:|.|..|..|.:..:|.|.  |.....|
Human   236 LQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNLTISASCYTPRADSFHIFRDAV 300

  Fly   265 IGN--------------TFYWTSLNAVHQTVVHRYM---SLPTLKMARASIAFLVVGAAF----- 307
            .|:              .:||    ..:|.:|.|.:   .:..:|.|....|:|.:...|
Human   301 TGDIPWPGIIFGMPITALWYW----CTNQVIVQRCLCGKDMSHVKAACIMCAYLKLLPMFLMVMP 361

  Fly   308 -FISLLCYLGLLIFHAYRDCDPLSAGLIMNDDQLVPLFVVNSLGHVYGMPGLFIAGIFGASLSSL 371
             .||.:.|..::......:|.......:...:...|..|:..:..  |:.||.::.:..:.:|||
Human   362 GMISRILYTDMVACVVPSECVKHCGVDVGCTNYAYPTMVLELMPQ--GLRGLMLSVMLASLMSSL 424

  Fly   372 SVYLNSTSLVILQDLVRGCFKMELGEWASTIVVKGSIVVLGLLAFAMVFV-LEKVS---GVLSIS 432
            :...||.|.:...||..   ||........:::.|.|.||.|...::|:| |.:||   .::..:
Human   425 TSIFNSASTLFTIDLYT---KMRKQASEKELLIAGRIFVLLLTVVSIVWVPLVQVSQNGQLIHYT 486

  Fly   433 VSLAAIAASSTFGIFTVGMLVPWANTVGTAVGGIASVLLTGWISFGSQFAAASGQLGSQRLPVSV 497
            .|:::........:|.:.:.....|..| |..|:...|..|.|...::||..:|
Human   487 ESISSYLGPPIAAVFVLAIFCKRVNEQG-AFWGLMVGLAMGLIRMITEFAYGTG----------- 539

  Fly   498 EGCLANASVAENAWVAEEEVFPLYRLSYHWISPIGVLTVVVVGSL-----VSLVTKPTDIKSLDS 557
             .|||.::.            |......|::.   ...|:..||:     :||:|||
Human   540 -SCLAPSNC------------PKIICGVHYLY---FSIVLFFGSMLVTLGISLLTKP-------- 580

  Fly   558 DLITPVIHRFLPKECFEQGNAEENSV 583
               .|.:|  |.:.|:...|:.|..:
Human   581 ---IPDVH--LYRLCWVLRNSTEERI 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31668	NP_001097055.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	122/552 (22%)
SLC5A4	XP_016884409.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146463
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750