Protein Alignment CG31668 and SLC5A3

DIOPT Version :9

• Sequence 1: NP_001097055.2
• Gene: CG31668 / 33395
• FlyBaseID: FBgn0051668
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_008864.4
• Gene: SLC5A3 / 6526
• HGNCID: 11038
• Length: 718
• Species: Homo sapiens
• Alignment Length: 616
• Identity: 135/616 - (21%)
• Similarity: 236/616 - (38%)
• Gaps: 161/616 - (26%)

  Fly     8 TVDYAVFLGVTILSIAIGLYFGFIRKSRNGPKTTTPTNEAPERRHQNFGSKKMNDYMMGSRNLRV 72
            |.|.|:.....||.:.|| :|...:.:|:                      .::.|.:..|::..
Human     7 TADIAIVALYFILVMCIG-FFAMWKSNRS----------------------TVSGYFLAGRSMTW 48

  Fly    73 FPVGMSLIASCISAVAIIGTPSEIYNYGTQYCFIVIA------LVLQGLAVSYIYLPVFSALQVT 131
            ..:|.||..|.|.:...||    :...|....|.|.|      |:||  .:.::::|::....|.
Human    49 VAIGASLFVSNIGSEHFIG----LAGSGAASGFAVGAWEFNALLLLQ--LLGWVFIPIYIRSGVY 107

  Fly   132 SSYEYLEMRF--HSAIRSIVSIIFILDVVLYLPFLAYLPALALNQVSGMNMYLIEAFIIVICVIY 194
            :..|||..||  |.......::..||.:...|....|..||.:.:..|.|:|:....:|.:..:.
Human   108 TMPEYLSKRFGGHRIQVYFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALL 172

  Fly   195 TVLGGLKAVVHTDIWQVVIMFASVLTIVVLATCYIDDQADFLEGLVRGGRLI------------F 247
            ||.|||.||::||..|.::|....||:::::...|..    .|.:.|...|.            .
Human   173 TVTGGLVAVIYTDTLQALLMIIGALTLMIISIMEIGG----FEEVKRRYMLASPDVTSILLTYNL 233

  Fly   248 SETNP--------------SPFARHTVW-SVVIGNT----FYWTSLNAVHQTVVHRYMSLPTLKM 293
            |.||.              :|......| ..::|.|    :||    ...|.:|.|.::...:..
Human   234 SNTNSCNVSPKKEALKMLRNPTDEDVPWPGFILGQTPASVWYW----CADQVIVQRVLAAKNIAH 294

  Fly   294 ARAS---IAFLVVGAAFFISLLCYLGLLIF----------HAYRDCDPLSAG--------LIMND 337
            |:.|   ..||.:...|.|.:...:..::|          |....|.. .||        |:|
Human   295 AKGSTLMAGFLKLLPMFIIVVPGMISRILFTDDIACINPEHCMLVCGS-RAGCSNIAYPRLVM-- 356

  Fly   338 DQLVPLFVVNSLGHVYGMPGLFIAGIFGASLSSLSVYLNSTSLVILQDLVRGCFKMELGEWAST- 401
             :|||:          |:.||.:|.:..|.:|.|....||.|.:...|:    :|: :.:.||:
Human   357 -KLVPV----------GLRGLMMAVMIAALMSDLDSIFNSASTIFTLDV----YKL-IRKSASSR 405

  Fly   402 -IVVKGSIVVLGLLAFAMVFV---LEKVSGVLSISVSLAA------IAASSTFGIFTVGMLVPW- 455
             :::.|.|.|..::..::.:|   :|...|.:.:.:...|      :||.....||       |
Human   406 ELMIVGRIFVAFMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIF-------WK 463

  Fly   456 -ANTVGTAVGGIASVLLTGWISFGSQFAAASGQLGSQRLPVSVEGCLANASVAENAWVAEEEVFP 519
             .|..|...||:|     |::            ||:.||.::...........:|.....:::..
Human   464 RCNEQGAFYGGMA-----GFV------------LGAVRLILAFAYRAPECDQPDNRPGFIKDIHY 511

  Fly   520 LY-RLSYHWISPIGVLTVVVVGSLVSLVTKP 549
            :| .....|::  |::||:     |||:|.|
Human   512 MYVATGLFWVT--GLITVI-----VSLLTPP 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31668	NP_001097055.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	126/595 (21%)
SLC5A3	NP_008864.4	SLC5sbd_SMIT	9..718	CDD:271382	134/614 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146451
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750