Protein Alignment CG31668 and Slc5a8

DIOPT Version :10

• Sequence 1: NP_001097055.2
• Gene: CG31668 / 33395
• FlyBaseID: FBgn0051668
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001178916.1
• Gene: Slc5a8 / 500820
• RGDID: 1564146
• Length: 611
• Species: Rattus norvegicus
• Alignment Length: 580
• Identity: 197/580 - (33%)
• Similarity: 318/580 - (54%)
• Gaps: 70/580 - (12%)

  Fly     1 MDTYR----FGTVDYAVFLGVTILSIAIGLYFGFIRKSRNGPKTTTPTNEAPERRHQNFGSKKMN 61
            ||..|    |...||.||.|:.::|.|||:|:.|   :..|.:|:                   .
  Rat     1 MDASRDIGSFVVWDYVVFAGMLLISAAIGIYYAF---AGGGQQTS-------------------K 43

  Fly    62 DYMMGSRNLRVFPVGMSLIASCISAVAIIGTPSEIYN-------YGTQYCFIVIALVLQGLAVSY 119
            |::||.|::...||.:||.||.:|||.::|||:|:|.       :|..|.|:|:       ..:.
  Rat    44 DFLMGGRSMSAVPVALSLTASFMSAVTVLGTPAEVYRFGAIFSIFGVTYFFVVV-------ISAE 101

  Fly   120 IYLPVFSALQVTSSYEYLEMRFHSAIRSIVSIIFILDVVLYLPFLAYLPALALNQVSGMNMYLIE 184
            ::||||..|.:||:|||||:||:..||...:::||:..:||...:.|.||||||||:|.:::...
  Rat   102 VFLPVFYRLGITSTYEYLELRFNRFIRLCGTVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAV 166

  Fly   185 AFIIVICVIYTVLGGLKAVVHTDIWQVVIMFASVLTIVVLATCYIDDQADFLEGLVRGGRLIFSE 249
            ....|:|..|..||||||||.||::||.||.|...::::.|:.........|.....||||.|..
  Rat   167 VATGVVCTFYCTLGGLKAVVWTDVFQVGIMVAGFASVIIQASITQGGINTILSDASNGGRLNFWN 231

  Fly   250 TNPSPFARHTVWSVVIGNTFYWTSLNAVHQTVVHRYMSLPTLKMARASIAFLVVGAAFFISLLC- 313
            .||:|..|||.|::::|.||.||::..|:|:.|.||:|..:...|:.|:...:||  .::.|:|
  Rat   232 FNPNPLQRHTFWTIIVGGTFTWTTIYGVNQSQVQRYISCKSRLHAKLSLYVNLVG--LWVILICS 294

  Fly   314 -YLGLLIFHAYRDCDPLSAGLIMNDDQLVPLFVVNSLGHVYGMPGLFIAGIFGASLSSLSVYLNS 377
             :.||.::..|.||||.::..:...|||:|..|::.|.:..|:||||:|..:..:||::|..:|:
  Rat   295 VFCGLALYSRYHDCDPWTSKKVSEVDQLMPYLVLDILKNYPGVPGLFVACAYSGTLSTVSSSINA 359

  Fly   378 TSLVILQDLVRGCFKMELGEWASTIVVKGSIVVLGLLAFAMVFVLEKVSGVLSISVSLAAIAASS 442
            .:.|.::||::..|| .|.|.:.:.:.:|..|:.|.|...|..|...:..:|..::|:..:....
  Rat   360 LAAVTVEDLIKPRFK-SLSEKSLSWISQGMSVLYGALCIGMAAVASLMGALLQAALSIFGMVGGP 423

  Fly   443 TFGIFTVGMLVPWANTVGTAVGGIASVLLTGWISFGSQFAAASGQLGSQRLPVSVE--GCLANAS 505
            ..|:|::|:|||:||:||...|.:|...::.|:..|:|...   .|..:.||:|:|  ||  |::
  Rat   424 LLGLFSLGILVPFANSVGAFAGLLAGFAVSLWVGIGAQLYP---PLPERTLPLSLETHGC--NST 483

  Fly   506 VAENAWVAEEEV------FPL------------YRLSYHWISPIGVLTVVVVGSLVSLVT 547
            .....|::..|:      |.:            |.|||.:.|.||.||.::||.|:||.|
  Rat   484 HNGTDWMSTTEMPFSTSAFQIHDVERSALMDNWYSLSYLYFSTIGTLTTLLVGILISLAT 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31668	NP_001097055.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	183/550 (33%)
Slc5a8	NP_001178916.1	SLC5sbd_SMCT1	7..549	CDD:271402	194/574 (34%)