DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31668 and Slc5a9

DIOPT Version :9

Sequence 1:	NP_001097055.2	Gene:	CG31668 / 33395	FlyBaseID:	FBgn0051668	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_001382057.1	Gene:	Slc5a9 / 366441	RGDID:	1311383	Length:	688	Species:	Rattus norvegicus

Alignment Length:	599	Identity:	133/599 - (22%)
Similarity:	237/599 - (39%)	Gaps:	136/599 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TVDYAVFLGVTILSIAIGLYFGFIRKSRNGPKTTTPTNEAPERRHQNFGSKKMNDYMMGSRNLRV 72
            |.|..|.:...:..:|:|:: ..||.||.                      .:..|.:..|::..
  Rat    34 TYDIVVVVIYFVFVLAVGIW-SSIRASRG----------------------TIGGYFLAGRSMTW 75

  Fly    73 FPVGMSLIASCISA---VAIIGTPS----EIYNYGTQYCFIVIALVLQGLAVSYIYLPVFSALQV 130
            :|:|.||::|.:.:   :.:.||.:    .:..:.....|:::||       .:|::||:.|..|
  Rat    76 WPIGASLMSSNVGSGLFIGLAGTGAAGGLAVGGFEWNATFLLLAL-------GWIFVPVYIAAGV 133

  Fly   131 TSSYEYLEMRFHSAIRSIVSIIFILDVVLYLPFL-----AYLPALALNQVSGMNMYLIEAFIIVI 190
            .:..:||:.||..  :.|...:.:|.::||: |.     .:..||.:....|.|:||....::|:
  Rat   134 VTMPQYLKKRFGG--QRIQVYMSVLSLILYI-FTKISTDIFSGALFIQMALGWNLYLSTVILLVV 195

  Fly   191 CVIYTVLGGLKAVVHTDIWQVVIMFASVLTIVVLATCYIDDQADFLE-GLVRGGRLIFSETNPSP 254
            ..:||:.|||.||::||..|.|||....|.::.|.         |.| |...|.:.::.::.|:.
  Rat   196 TAVYTIAGGLTAVIYTDALQTVIMVGGALVLMFLG---------FREVGWYPGLQQLYRQSIPNV 251

  Fly   255 FARHTV---------------------W-SVVIGNTFYWTSLNAVHQTVVHRYMSLPTLKMARAS 297
            ...:|.                     | .::.|.|...|......|.:|.|.:|..:|..|:..
  Rat   252 TVPNTTCHLPRSDAFHMLRDPVNGDIPWPGLIFGLTVLATWCWCTDQVIVQRSLSAKSLSHAKGG 316

  Fly   298 I---AFLVVGAAFFISLLCYLGLLIFHAYRD---------CDPLSAGLIMNDDQLVPLFVVNSLG 350
            .   .:|.:...|||.:   .|::....|.|         |..:....:...:...|..|:..:
  Rat   317 SVLGGYLKILPMFFIVM---PGMISRALYPDEVACVDPDICQRVCGARVGCSNIAYPKLVMALM- 377

  Fly   351 HVYGMPGLFIAGIFGASLSSLSVYLNSTSLVILQDLVRGCFKMELGEWASTIVVKGSIVVLGLLA 415
             ..|:.||.||.|..|.:|||:...||:|.:...|:.:. .:.:..|....:|.:..:|.|.|::
  Rat   378 -PVGLRGLMIAVIMAALMSSLTSIFNSSSTLFAIDVWQR-VRRQASEQELMVVGRLFVVFLVLIS 440

  Fly   416 FAMVFVLEKV-SGVL-----SISVSLA-AIAASSTFGIFTVGMLVP---WANTVGTAVGGIASVL 470
            ...:.:::.. ||.|     ||:..|| .|.|.....||...:..|   |....|..||.:..:|
  Rat   441 ILWIPIIQSSNSGQLFDYIQSITSYLAPPITALFLLAIFCKRVTEPGAFWGLMFGLVVGILRMIL 505

  Fly   471 LTGWISFGSQFAAASGQLGSQRLPVSVEGCLANASVAENAWVAEEEVFPLYRLSYHWISPIGVLT 535
                 .| |..|.|.|:  ..|.|.                     |...:...|..:...|:..
  Rat   506 -----EF-SYSAPACGE--KDRRPA---------------------VLKDFHYLYFALLLCGLTA 541

  Fly   536 VVVVGSLVSLVTKP 549
            :::|  ::|..|:|
  Rat   542 IIIV--IISFFTEP 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31668	NP_001097055.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	127/578 (22%)
Slc5a9	NP_001382057.1	SLC5-6-like_sbd	48..688	CDD:382020	130/585 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340196
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.850