DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31668 and Slc5a6

DIOPT Version :9

Sequence 1:	NP_001097055.2	Gene:	CG31668 / 33395	FlyBaseID:	FBgn0051668	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_001171092.1	Gene:	Slc5a6 / 330064	MGIID:	2660847	Length:	634	Species:	Mus musculus

Alignment Length:	587	Identity:	192/587 - (32%)
Similarity:	301/587 - (51%)	Gaps:	54/587 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 FGTVDYAVFLGVTILSIAIGLYFGFIRKSRNGPKTTTPTNEAPERRHQNFGSKKMNDYMMGSRNL 70
            |..|||.||..:.:||:.||||...                      :.:|...:.:.:|..|.:
Mouse    23 FSVVDYVVFGLLLVLSLVIGLYHAC----------------------RGWGHHTVGELLMADRKM 65

  Fly    71 RVFPVGMSLIASCISAVAIIGTPSEIYNYGTQYCFIVIALVLQGLAVSYIYLPVFSALQVTSSYE 135
            ...||.:||:|:..|||||:|.|:||:.:||||.|:..:..|..|..::|::|||..|.:||:||
Mouse    66 GCLPVALSLLATFQSAVAILGAPAEIFRFGTQYWFLGCSYFLGLLIPAHIFIPVFYRLHLTSAYE 130

  Fly   136 YLEMRFHSAIRSIVSIIFILDVVLYLPFLAYLPALALNQVSGMNMYLIEAFIIVICVIYTVLGGL 200
            |||:||:.|:|...::.||..:|:|:....|.|:||||.|:|.:::|....:.::|.|||.||||
Mouse   131 YLELRFNKAVRICGTVTFIFQMVIYMGVALYAPSLALNAVTGFDLWLSVLALGIVCNIYTALGGL 195

  Fly   201 KAVVHTDIWQVVIMFASVLTIVVLATCYIDD-----QADFLEGLVRGGRLIFSETNPSPFARHTV 260
            |||:.||::|.::||...|.::::....:..     ......||:.|..|     :|.||.|||.
Mouse   196 KAVIWTDVFQTLVMFLGQLVVIIVGAARVGGLGHVWNVTSQHGLISGINL-----DPDPFVRHTF 255

  Fly   261 WSVVIGNTFYWTSLNAVHQTVVHRYMSLPTLKMARASIAFLVVGAAFFISLLCYLGLLIFHAYRD 325
            |::..|..|...||..|:|..|.||:|..:.:.|..|...:.......:.:.|.:||::| ||.:
Mouse   256 WTLAFGGVFMMLSLYGVNQAQVQRYLSSHSERAAVLSCYAVFPCQQVALCMSCLIGLVMF-AYYN 319

  Fly   326 CDPLSAGLIM-NDDQLVPLFVVNSLGHVYGMPGLFIAGIFGASLSSLSVYLNSTSLVILQDLVRG 389
            ...:|..|.. ..||||..||::.|..:.|:||||:|.:|..|||::|...||.:.|.::||::.
Mouse   320 MYSMSPELKQAAPDQLVLYFVMDLLKDMPGLPGLFVACLFSGSLSTISSAFNSLATVTMEDLIQP 384

  Fly   390 CFKMELGEWASTIVVKGSIVVLGLLAFAMVFVLEKVSGVLSISVSLAAIAASSTFGIFTVGMLVP 454
            .|. :|.|..:.::.:|.....||:...|.::...:..||..::|:..:......|:|.:|:..|
Mouse   385 WFP-QLTETRAIMLSRGLAFAYGLVCLGMAYISSHLGSVLQAALSIFGMVGGPLLGLFCLGLFFP 448

  Fly   455 WANTVGTAVGGIASVLLTGWISFGSQFAAASGQLGSQRLPVSVEGCLANASVAENAWVAEEEVFP 519
            .||.:|..||.:..:.:..||..||..:..|..:....|..|.....||.:||     |...|.|
Mouse   449 CANPLGAIVGLLTGLTMAFWIGIGSIVSRMSSAVAPPPLNGSSSFLPANVTVA-----AVTTVMP 508

  Fly   520 -----------LYRLSYHWISPIGVLTVVVVGSLVSLVTKPTDIKSLDSDLITPVIHR---FLPK 570
                       .|.|||.|.|.....||:|||.:|||:|.....:||:...|.||:.:   .||.
Mouse   509 STLSKPTGLQHFYSLSYLWYSAHNSTTVIVVGLIVSLLTGGMRGRSLNPGTIYPVLPKLLALLPL 573

  Fly   571 EC 572
            .|
Mouse   574 SC 575

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31668	NP_001097055.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	174/538 (32%)
Slc5a6	NP_001171092.1	SLC5-6-like_sbd	23..548	CDD:320982	183/558 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I12033
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.820