DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31668 and Slc5a11

DIOPT Version :9

Sequence 1:	NP_001097055.2	Gene:	CG31668 / 33395	FlyBaseID:	FBgn0051668	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_666310.1	Gene:	Slc5a11 / 233836	MGIID:	1919316	Length:	673	Species:	Mus musculus

Alignment Length:	530	Identity:	125/530 - (23%)
Similarity:	204/530 - (38%)	Gaps:	135/530 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 DYAVFLGVTILSIAIGLYFGFIRKSRNGPKTTTPTNEAPERRHQNFGSKKMNDYMMGSRNLRVFP 74
            |.||.:...:..:|:||: ..:|..|:..|                      .|.:...::..:|
Mouse    28 DIAVLVLYFLFVLAVGLW-STVRTKRDTVK----------------------GYFLAGGDMVWWP 69

  Fly    75 VGMSLIASCISAVAIIGTPSEIYNYGTQYCFIVIALVLQG----LAVSYIYLPVFSALQVTSSYE 135
            ||.||.||.:.:...||    :...|......|.|..|.|    |.:::::||::.|.|||:..|
Mouse    70 VGASLFASNVGSGHFIG----LAGSGAAVGISVAAYELNGLFSVLMLAWVFLPIYIAGQVTTMPE 130

  Fly   136 YLEMRFHSAIRSIVSIIFILDVVLYLPFLA--YLPALALNQVSGMNMYLIEAFIIVICVIYTVLG 198
            ||..||.....||...:..|.:.::.....  |..|:.:.|...:::||....::.|..:|||.|
Mouse   131 YLRRRFGGNRISITLAVLYLFIYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAITALYTVAG 195

  Fly   199 GLKAVVHTDIWQVVIM-----------FASVLTIVVLATCYIDDQADFLE-----------GLVR 241
            ||.||::||..|.|||           ||:|..:..|...|      ||.           ||.|
Mouse   196 GLAAVIYTDALQTVIMLIGAFILMGYSFAAVGGMEGLKDQY------FLALASNRSENSSCGLPR 254

  Fly   242 GGRL-IFSETNPSPFARHTVW-----SVVIGNTFYWTSLNAVHQTVVHRYMSLPTLKMARAS--- 297
            .... ||.:    |......|     .:.|.:.:||    ...|.:|.|.::...|..|:..
Mouse   255 EDAFHIFRD----PLTSDLPWPGILFGMSIPSLWYW----CTDQVIVQRSLAAKNLSHAKGGSLM 311

  Fly   298 IAFLVVGAAFFISLLCYLGLL--------IFHAYRD-CDPLSAGLIMNDDQLVPLFVVNSLGHVY 353
            .|:|.|...|   |:.:.|::        :..|:.| |..:.:......|...|..|:..|  ..
Mouse   312 AAYLKVLPLF---LMVFPGMVSRVLFPDQVACAHPDICQRVCSNPSGCSDIAYPKLVLELL--PT 371

  Fly   354 GMPGLFIAGIFGASLSSLSVYLNSTSLVILQDLVRGCFKMELGEW------AS--TIVVKGSIVV 410
            |:.||.:|.:..|.:|||:...||.|.:...||           |      ||  .:::.|.|.|
Mouse   372 GLRGLMMAVMVAALMSSLTSIFNSASTIFTMDL-----------WNHIRPRASERELMIVGRIFV 425

  Fly   411 LGLLAFAMVFV--------------LEKVSGVLSISVSLAAIAASSTFGIFTVGMLVPWANTVGT 461
            ..|:..:::::              ::.:|..|...|::          :|.:|......|..|.
Mouse   426 FALVLVSILWIPIVQASQGGQLFIYIQSISSYLQPPVAM----------VFIMGCFWKRTNEKGA 480

  Fly   462 AVGGIASVLL 471
            ..|.|..:||
Mouse   481 FSGLILGLLL 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31668	NP_001097055.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	125/530 (24%)
Slc5a11	NP_666310.1	SLC5-6-like_sbd	28..673	CDD:382020	125/530 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836565
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750