Protein Alignment CG31668 and SLC5A9

DIOPT Version :10

• Sequence 1: NP_001097055.2
• Gene: CG31668 / 33395
• FlyBaseID: FBgn0051668
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_047304539.1
• Gene: SLC5A9 / 200010
• HGNCID: 22146
• Length: 745
• Species: Homo sapiens
• Alignment Length: 669
• Identity: 157/669 - (23%)
• Similarity: 250/669 - (37%)
• Gaps: 183/669 - (27%)

  Fly     9 VDYAVFLGVTILSIAIGLYFG----FIRKSRNGPKTTTPTNEAPERRHQNFGSKKMNDYMMGSRN 69
            |...:|:|:.....|.||..|    .:||||:|                            |.|.
Human    88 VGSGLFIGLAGTGAAGGLAVGGFEWNMRKSRSG----------------------------GDRG 124

  Fly    70 LRVFPVGMSLIASCISAVAIIGTPSEIYNYGTQYCFIV---IALVLQG----------------L 115
            :.....|.:.:.|.:|..::.|.|:      .|:|..|   .::.:|.                |
Human   125 IHPRSHGRTGVRSQVSYFSVRGPPT------AQHCLWVGSRPSVYIQDLDTFFFSPLSQATWLLL 183

  Fly   116 AVSYIYLPVFSALQVTSSYEYLEMRFHSAIRSIVSIIFILDVVLYLPFL-----AYLPALALNQV 175
            |:.::::||:.|..|.:..:||:.||..  :.|...:.:|.::||: |.     .:..||.:...
Human   184 ALGWVFVPVYIAAGVVTMPQYLKKRFGG--QRIQVYMSVLSLILYI-FTKISTDIFSGALFIQMA 245

  Fly   176 SGMNMYLIEAFIIVICVIYTVLGGLKAVVHTDIWQVVIMFASVLTIVVLATCYIDDQADFLEGLV 240
            .|.|:||....::|:..:||:.|||.||::||..|.|||....|.::.|..    ....:..||.
Human   246 LGWNLYLSTGILLVVTAVYTIAGGLMAVIYTDALQTVIMVGGALVLMFLGF----QDVGWYPGLE 306

  Fly   241 RGGRLIFSETN--------PSPFARHTV---------W-SVVIGNTFYWTSLNAVHQTVVHRYMS 287
            :..|.......        |.|.|.|.:         | .::.|.|...|......|.:|.|.:|
Human   307 QRYRQAIPNVTVPNTTCHLPRPDAFHILRDPVSGDIPWPGLIFGLTVLATWCWCTDQVIVQRSLS 371

  Fly   288 LPTLKMARASI---AFLVVGAAFFISLLCYLGLLIFHAYRDC-DP--------LSAG-------- 332
            ..:|..|:...   .:|.:...|||.:...:...:|.....| ||        ...|
Human   372 AKSLSHAKGGSVLGGYLKILPMFFIVMPGMISRALFPDEVGCVDPDVCQRICGARVGCSNIAYPK 436

  Fly   333 LIMNDDQLVPLFVVNSLGHVYGMPGLFIAGIFGASLSSLSVYLNSTSLVILQDLVRGCFKMELGE 397
            |:|   .|:|:          |:.||.||.|..|.:|||:...||:|.:...|:.:. |:.:..|
Human   437 LVM---ALMPV----------GLRGLMIAVIMAALMSSLTSIFNSSSTLFTIDVWQR-FRRKSTE 487

  Fly   398 WASTIVVKGSIVVLGLLAFAMVF---VLEKVSGVL-----SISVSLA-AIAASSTFGIFTVGMLV 453
              ..::|.|.:.|:.|:..::::   :....||.|     :::..|| .|.|.....||...:..
Human   488 --QELMVVGRVFVVFLVVISILWIPIIQSSNSGQLFDYIQAVTSYLAPPITALFLLAIFCKRVTE 550

  Fly   454 P---WANTVGTAVGGIASVLLTGWISFGSQFAAASGQLGSQRLPVSVEGCLANASVAENAWVAEE 515
            |   |....|..||     ||...:.| |..|.|.|::  .|.|.
Human   551 PGAFWGLVFGLGVG-----LLRMILEF-SYPAPACGEV--DRRPA-------------------- 587

  Fly   516 EVFPLYRLSYHWISPIGVLTVVVVGSLVSLVTKPTDIKSLD-----------SDL------ITPV 563
             |...:...|..|...|:..:|:|  :|||.|.|...:.|.           |:|      .||.
Human   588 -VLKDFHYLYFAILLCGLTAIVIV--IVSLCTTPIPEEQLTRLTWWTRNCPLSELEKEAHESTPE 649

  Fly   564 IHRFLPKECFEQGNAEENS 582
            |......||...|.|.|||
Human   650 ISERPAGECPAGGGAAENS 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31668	NP_001097055.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	136/599 (23%)
SLC5A9	XP_047304539.1	SLC5sbd_SGLT4	37..745	CDD:271380	157/669 (23%)