Protein Alignment CG31668 and SLC5A10

DIOPT Version :10

• Sequence 1: NP_001097055.2
• Gene: CG31668 / 33395
• FlyBaseID: FBgn0051668
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_016879680.2
• Gene: SLC5A10 / 125206
• HGNCID: 23155
• Length: 649
• Species: Homo sapiens
• Alignment Length: 697
• Identity: 150/697 - (21%)
• Similarity: 259/697 - (37%)
• Gaps: 200/697 - (28%)

  Fly     2 DTYRFGT-VDYAVFLGVTI---LSIAIGLYFGFIRKSRNGPKTTTPTNEAPERRHQNFGSKKMND 62
            |.:..|| :..|..:.:|:   |::|:|:: ...|.|||                      .:|.
Human     8 DLHTPGTQLSVADIIVITVYFALNVAVGIW-SSCRASRN----------------------TVNG 49

  Fly    63 YMMGSRNLRVFPVGMSLIASCISAVAIIGTPSE-------IYNYGTQYCFIVIALVLQGLAVSYI 120
            |.:..|::..:|:|.||.||...:...||....       :..:.....::::||       :::
Human    50 YFLAGRDMTWWPIGASLFASSEGSGLFIGLAGSGAAGGLAVAGFEWNATYVLLAL-------AWV 107

  Fly   121 YLPVFSALQVTSSYEYLEMRF-HSAIRSIVSII-FILDVVLYLPFLAYLPALALNQVSGMNMYLI 183
            ::|::.:.::.:..||::.|: ...||..:|:: .:|.|...:....|..||.::...|.|.||.
Human   108 FVPIYISSEIVTLPEYIQKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLS 172

  Fly   184 EAFIIVICVIYTVLGGLKAVVHTDIWQVVIMF--ASVLTI------------------------V 222
            ....:.|..:||:.|||.||::||..|.:||.  |.:|||                        :
Human   173 TILTLGITALYTIAGGLAAVIYTDALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTI 237

  Fly   223 VLATCYIDDQADFLEGLVRGGRLIFSE--TNPSPFARHTVWSVVIGNTFYWTSLNAVHQTVVHRY 285
            ...||:: .:.|.:.        :|.:  |...|:...| :.:.|..|:||    ...|.:|.|.
Human   238 ANTTCHL-PRTDAMH--------MFRDPHTGDLPWTGMT-FGLTIMATWYW----CTDQVIVQRS 288

  Fly   286 MSLPTLKMARASIAFLVVGAAFFISLLCYLGLLIF------------HAYRDCDPLSAGLIMNDD 338
            :|...|..|:|....     |.::.:| .:||:|.            |.|.:...:|.....:..
Human   289 LSARDLNHAKAGSIL-----ASYLKML-PMGLIIMPGMISRALFPGAHVYEERHQVSVSRTDDVG 347

  Fly   339 QLVPLFVVNSLGHVYG-------------MP----GLFIAGIFGASLSSLSVYLNSTSLVILQDL 386
            .:||...:.:.|...|             ||    ||.||.:..|.:|||:...||:|.:...|:
Human   348 CVVPSECLRACGAEVGCSNIAYPKLVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDI 412

  Fly   387 VRGCFKMELGEWASTIVVKGSI-----------------------VVLGLLAFAMVFVLEKVSGV 428
            .|. .:...||....:|.:..|                       .:|||:...:..|:..:.||
Human   413 WRR-LRPRSGERELLLVGRTGIPSTPPAPQSRLSFLLPETPPLERYLLGLVVMDLWLVIVALIGV 476

  Fly   429 LSISVSLAAIAASSTFG-------------------IFTVGMLVPWANTVGTAVGGIASVLLTGW 474
               ||:...:...|..|                   :|.:|:....||..| |..|:.:.|:.|.
Human   477 ---SVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQG-AFWGLIAGLVVGA 537

  Fly   475 ISFGSQFAAASGQLGSQRLPVSVEGCLANASVAENAWVAEEEVFPLYRLSYHWISPIGVLTVVVV 539
            .....:|...:...|......:|.|.:.....|    ||      |:.||.         .|||.
Human   538 TRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFA----VA------LFALSG---------AVVVA 583

  Fly   540 GSLVSLVTKPTDIKSLD--------------SDLITPVIHRFLPKEC 572
            |||::...:...|::|.              .|..||..|.|..:.|
Human   584 GSLLTPPPQSVQIENLTWWTLAQDVPLGTKAGDGQTPQKHAFWARVC 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31668	NP_001097055.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	133/632 (21%)
SLC5A10	XP_016879680.2	SLC5-6-like_sbd	17..649	CDD:444915	147/688 (21%)