Protein Alignment CG31668 and slc5a11

DIOPT Version :10

• Sequence 1: NP_001097055.2
• Gene: CG31668 / 33395
• FlyBaseID: FBgn0051668
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_004918107.1
• Gene: slc5a11 / 100488766
• XenbaseID: XB-GENE-1010719
• Length: 674
• Species: Xenopus tropicalis
• Alignment Length: 629
• Identity: 149/629 - (23%)
• Similarity: 248/629 - (39%)
• Gaps: 159/629 - (25%)

  Fly     8 TVDYAVFLGVTILSIAIGLYFGFIRKSRNGPKTTTPTNEAPERRHQNFGSKKMNDYMMGSRNLRV 72
            |||..|.:...:..:.:||:  .|.:::.|                     .:..|.:..:::..
 Frog    25 TVDIVVLVLYFVFVLGVGLW--SICRTKRG---------------------TVKGYFLAGKDMAW 66

  Fly    73 FPVGMSLIASCISAVAIIGTPSE---------IYNYGTQYCFIVIALVLQGLAVSYIYLPVFSAL 128
            :|||.||.||.:.:...||....         .|.:...:|.         ||:::::||::.:.
 Frog    67 WPVGASLFASNVGSGHFIGLAGSGAASGIAVTAYEWNGLFCV---------LALAWLFLPIYISA 122

  Fly   129 QVTSSYEYLEMRFHSAIRSIVSIIFILDVVLYLPFLA--YLPALALNQVSGMNMYLIEAFIIVIC 191
            .||:..|||:.||......|...|..|.:.::.....  |..||.:.|....::|:....::||.
 Frog   123 GVTTMPEYLQRRFGGKRIQIFLAILYLFIYIFTKISVDMYAGALFIQQALQWDLYVAVIGLLVIT 187

  Fly   192 VIYTVLGGLKAVVHTDIWQVVIMFASVLTIVVLATCYIDD------QADFLE------------G 238
            .||||.|||.||::||..|.|||....|  :::|..:|:.      |..:.:            |
 Frog   188 AIYTVAGGLAAVIYTDTLQTVIMIIGAL--ILMAYSFIEIGGFEALQEKYFQAIPNTHSGNSTCG 250

  Fly   239 LVRGGRL-IFSETNPSPFARHTVW-SVVIGNT----FYWTSLNAVHQTVVHRYMSLPTLKMARAS 297
            :.|.... ||.:    |......| .|::|.|    :||    ...|.:|.|.:|...|..|:..
 Frog   251 IPREDAFHIFRD----PVTSDLPWPGVLVGMTIPSLWYW----CTDQVIVQRSLSAKNLSHAKGG 307

  Fly   298 ---IAFLVVGAAFFISLLCYLGLLIFHAYRDC-DP-LSAGLIMN----DDQLVPLFVVNSLGHVY 353
               .|.|.|...|.:.|...:..::|.....| || |...:..|    .|...|..|:..|  ..
 Frog   308 SLLAASLKVLPLFMMVLPGMISRVLFTDQVACADPELCKEICGNPSGCSDIAYPKMVIELL--PT 370

  Fly   354 GMPGLFIAGIFGASLSSLSVYLNSTSLVILQDLVRGCFKMELGEWASTIVVKGSIVVLGLLAFAM 418
            |:.||.::.:..|.:|||:...||.|.:...||.|. .:....||...||  |.:.||.|:..::
 Frog   371 GLRGLMMSVMIAALMSSLTSIFNSASTIFTMDLWRH-IRPRSTEWELMIV--GRVFVLALVVVSI 432

  Fly   419 VFV--------------LEKVSGVLSISVSLAAIAA-----SSTFGIFTVGMLVPWANTVGTAVG 464
            :::              ::.:|..|...|::..||.     ::..|.|       |..|:|.|||
 Frog   433 LWIPLVQASQGGQLFIYIQSISSYLQPPVAVVFIAGCFWKRTNEKGAF-------WGMTIGLAVG 490

  Fly   465 GIASVLLTGWISFGSQFAAASGQLGSQRLPVSVEGCLANASVAENAWVAEEEVFPLYRLSYHWIS 529
            .|..||         .|...:.|...   |.:..|.:.                   .:.|.::|
 Frog   491 LIRMVL---------DFIYVAPQCDQ---PDTRPGVVK-------------------YVHYLYLS 524

  Fly   530 PI-GVLTVVVVGSLVSLVTKP---------TDIKSLDSDLITPV 563
            .| |:||::||.: ||:.|:|         |.....|::::.||
 Frog   525 MILGLLTLIVVVA-VSIWTEPPSKQMISRLTWFSRFDTEVVGPV 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31668	NP_001097055.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	134/584 (23%)
slc5a11	XP_004918107.1	SLC5sbd_SGLT6	27..674	CDD:271381	147/627 (23%)