DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment aop and elk1

DIOPT Version :9

Sequence 1:	NP_001259908.1	Gene:	aop / 33392	FlyBaseID:	FBgn0000097	Length:	732	Species:	Drosophila melanogaster
Sequence 2:	XP_696294.3	Gene:	elk1 / 567895	ZFINID:	ZDB-GENE-090529-5	Length:	521	Species:	Danio rerio

Alignment Length:	413	Identity:	103/413 - (24%)
Similarity:	159/413 - (38%)	Gaps:	140/413 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   398 LWDFLQQLLNDRNQKYSDLIAWKCRDTGVFKIVDPAGLAKLWGIQKNHLSMNYDKMSRALRYYYR 462
            ||.||..||:|:|||:  ||:|...| |.||::|...:|:|||::||..:|||||:||||||||.
Zfish    16 LWQFLLHLLDDQNQKH--LISWTSGD-GEFKLLDAEEVARLWGLRKNKTNMNYDKLSRALRYYYD 77

  Fly   463 VNILRKVQGERHCYQFLR--NPTELKNIK------------NISLLRQSTPANG----------- 502
            .||::||.|::..|:|:.  :|.....:|            .:.|..|:.|..|
Zfish    78 KNIIKKVSGQKFVYKFVTYPDPNSADGLKGTEDSQRASTGEKLELSIQTKPMGGATTANQCLSKS 142

  Fly   503 ---NGGSPSMPQGSS------------------QAP------------------GSPA------- 521
               ...|||..|.||                  |.|                  ..||
Zfish   143 LQVQRSSPSSVQRSSRNDYMKSGLYSTFTIQSLQTPCKGNSKLIKTEHVLNDCNPKPASLDRTMH 207

  Fly   522 --------GQNWNPQQQSQQQQQSPQRPASRNGPMSLPAVAAVAAAAAAAYGPPPTSPLFMHAIN 578
                    ||..:.|.||..:..:.|...::..|.:.||::....:.:|.            ||.
Zfish   208 EMRVCQTEGQQGSVQAQSTVESSNLQVIVTQPSPCATPALSPQTPSGSAT------------AIT 260

  Fly   579 GAFHYLSAAAAGPPPNSPALNTPSAVGG-----PDKFQFHPLKLENGSGSGSESAGEDLKPTDLS 638
            ......|.:...||  ...|:.||::..     |.:...:|          |:.....:||..:.
Zfish   261 NNQAQKSQSLGDPP--QIYLSDPSSLTSLIPLPPGECVVNP----------SQHVFVVIKPPSVG 313

  Fly   639 VSSKSTATSNEDCYPLIRNADGLTTIKLIRYNEHQVAASPAGQSPKHDDQQAGASNASSSPRPMD 703
            .|.:|:.:::||...::...|        :.:...|:|.|.          .|.::|   |.|:|
Zfish   314 QSKESSLSADEDLLEIVSLED--------KADVEPVSAVPV----------PGVTDA---PIPVD 357

  Fly   704 QASEQAQPV--PMESDCNGGESE 724
            ..|...:||  |:      ||.|
Zfish   358 ATSPCVEPVGPPV------GEGE 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
aop	NP_001259908.1	SAM_PNT-Tel_Yan	49..116	CDD:176085
aop	NP_001259908.1	ETS	395..482	CDD:197710	44/85 (52%)
elk1	XP_696294.3	ETS	13..98	CDD:197710	44/84 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910