Protein Alignment aop and Elf4

DIOPT Version :9

• Sequence 1: NP_001259908.1
• Gene: aop / 33392
• FlyBaseID: FBgn0000097
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_001368805.1
• Gene: Elf4 / 56501
• MGIID: 1928377
• Length: 655
• Species: Mus musculus
• Alignment Length: 517
• Identity: 134/517 - (25%)
• Similarity: 210/517 - (40%)
• Gaps: 119/517 - (23%)

  Fly   222 TNTSNPTSSSASSTG--SNGSQP-NIMPMKGISSASSNHSDSEEEYSETSGGVSKMPPAPLSYST 283
            |:....||::.|||.  .|.:.| :::..|.|.|:....|||      .|.....:|...||
Mouse    81 TDDDVSTSNNVSSTEVLFNVATPSDVLDEKQIFSSPEVLSDS------NSVQAINLPNFLLS--- 136

  Fly   284 ASPPGTPILKDIKPNWTQQLTNSFVNSWSQQQQQQQQQQAAAVAAVAAQAQQHQLQQQQQQQQLP 348
                 ||...|:|.          .:....|::..::::.         :::..|::..:.::..
Mouse   137 -----TPEPDDLKK----------TSDAGDQKEHSEEEKV---------SREENLRKMGKARKRN 177

  Fly   349 QKLTLDNTAGPVVTPAGGSISAPTTPSYMYKAKREFFPENSEPNTNGR----LLWDFLQQLLNDR 409
            :|...:.:..||           |.||...:.|          :.:|:    .||:||..||.||
Mouse   178 RKTKNNRSTSPV-----------TDPSMPIRKK----------SKDGKGSTIYLWEFLLALLQDR 221

  Fly   410 N--QKYSDLIAWKCRDTGVFKIVDPAGLAKLWGIQKNHLSMNYDKMSRALRYYYRVNILRKVQGE 472
            |  .||   |.|..|:.|:||:||...::||||.|||...|||:.|.|||||||:..||.||:|:
Mouse   222 NTCPKY---IKWTQREKGIFKLVDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQRGILAKVEGQ 283

  Fly   473 RHCYQFLRNPTELKNIKNISLLRQSTPANGNGGSPSMPQGSSQAPGSPAGQNWNPQQQSQQ--QQ 535
            |..|||...|.:|..|            :....||..|:.||||..|........::.|.:  .:
Mouse   284 RLVYQFKEMPKDLVVI------------DDEEESPETPEDSSQASTSSTPSTSTIRRASSRVGTR 336

  Fly   536 QSPQRPASRNGPMSLPAV--AAVAAAAAAAYG------PPPTSPLFMHAINGAFHYLSAAAAGPP 592
            .||:  ...|.|...|.|  ..:..:|:...|      .|.||.:....:..........::.|.
Mouse   337 ASPE--DKDNPPWEKPKVQHTGLQPSASLELGLSVDEEVPTTSTMLASPLQSQARLTKTVSSSPA 399

  Fly   593 PNSPALN-TPSAVGGPDKFQFHPLK--LENGSGSGSESAGEDLKPTDLSVSSKSTATSNEDCYPL 654
            |::..|. .|...|.....|..||.  |.||..:.:.:      ||.|.:.|....::.:|.:.|
Mouse   400 PSNIHLGVAPVGPGSTVTLQTIPLTTVLTNGPPASTTA------PTQLVLQSVPQVSTFKDTFTL 458

  Fly   655 IRNADGLTTIKLIRYNEHQVA--ASP----------AGQSPKHD---DQQAGASNASSSPRP 701
             :.:..|.|    ...|:|||  .:|          ||.:|:.:   .|..||.:|..|.:|
Mouse   459 -QTSFPLNT----NLQENQVATQGAPLILSGLPQLLAGANPQSNPAPSQVIGAGSAGPSSQP 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aop	NP_001259908.1	SAM_PNT-Tel_Yan	49..116	CDD:176085
		ETS	395..482	CDD:197710	47/92 (51%)
Elf4	NP_001368805.1	Elf-1_N	2..103	CDD:403506	7/21 (33%)
		RUNX1-binding. /evidence=ECO:0000250|UniProtKB:Q99607	86..205		31/172 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	136..202		14/113 (12%)
		Ets	209..289	CDD:395126	44/82 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	301..362		15/62 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	493..512		5/18 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3804
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810