Protein Alignment aop and ETV7

DIOPT Version :10

• Sequence 1: NP_523455.2
• Gene: aop / 33392
• FlyBaseID: FBgn0000097
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_057219.1
• Gene: ETV7 / 51513
• HGNCID: 18160
• Length: 341
• Species: Homo sapiens
• Alignment Length: 508
• Identity: 120/508 - (23%)
• Similarity: 175/508 - (34%)
• Gaps: 217/508 - (42%)

  Fly    10 QLSLNSLNPGIWSDVLWRCPPAPSSQLAELKTQ-----------LPPSLPSDPRLWSREDVLVFL 63
            :|:::.::|      :...||..:...|..:.|           ||..|...|.||||||||.:|
Human     5 ELAISPISP------VAAMPPLGTHVQARCEAQINLLGEGGICKLPGRLRIQPALWSREDVLHWL 63

  Fly    64 RFCVREFDLPKLDFDLFQMNGKALCLLTRADFGHRCPGAGDVLHNVLQMLIIESHMMQWHLPNSP 128
            |:..:|:.||......|:|||:|||:||:.||.||.|.:||||:.:||.:
Human    64 RWAEQEYSLPCTAEHGFEMNGRALCILTKDDFRHRAPSSGDVLYELLQYI--------------- 113

  Fly   129 VTPTSRYPL-------------SPHSHPPTPTWPPLNAPPENSPFHSSAHSLAGHHFMAPNSVTL 180
              .|.|..|             :|..|.|        .|||.....|...:..||        .|
Human   114 --KTQRRALVCGPFFGGIFRLKTPTQHSP--------VPPEEVTGPSQMDTRRGH--------LL 160

  Fly   181 SPPPSVDSQASSPPQAPYQNGGATGAAPGSAGGSAPAAGGATNTSNPTSSSASSTGSNGSQPNIM 245
            .||.                       ||.             |||
Human   161 QPPD-----------------------PGL-------------TSN------------------- 170

  Fly   246 PMKGISSASSNHSDSEEEYSETSGGVSKMPPAPLSYSTASPPGTPILKDIKPNWTQQLTNSFVNS 310
                     ..|.|.                          ||.       ..||
Human   171 ---------FGHLDD--------------------------PGL-------ARWT---------- 183

  Fly   311 WSQQQQQQQQQQAAAVAAVAAQAQQHQLQQQQQQQQLPQKLTLDNTAGPVVTPAGGSISAPTTPS 375
                ..:::.......|.:..:.|                               |..|.|..|.
Human   184 ----PGKEESLNLCHCAELGCRTQ-------------------------------GVCSFPAMPQ 213

  Fly   376 YMYKAKREFFPENSEPNTNGRLLWDFLQQLLNDRNQKYSDLIAWKCRDTGVFKIVDPAGLAKLWG 440
            .....:          ..:.|||||::.|||.|  .:|...|.|:.:|..:|::|||.|||:|||
Human   214 APIDGR----------IADCRLLWDYVYQLLLD--TRYEPYIKWEDKDAKIFRVVDPNGLARLWG 266

  Fly   441 IQKNHLSMNYDKMSRALRYYYRVNILRKVQGERHCYQFLRNPTELKNIKNISL 493
            ..||.::|.|:|||||||:||::||::|..|::..::||:.|.::...|:..|
Human   267 NHKNRVNMTYEKMSRALRHYYKLNIIKKEPGQKLLFRFLKTPGKMVQDKHSHL 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aop	NP_523455.2	SAM_PNT-Tel_Yan	49..116	CDD:176085	34/66 (52%)
		ETS	395..482	CDD:197710	42/86 (49%)
ETV7	NP_057219.1	SAM_PNT-Tel_Yan	49..116	CDD:176085	34/83 (41%)
		ETS	223..308	CDD:197710	42/86 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	315..341		2/5 (40%)