DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment aop and Ets21C

DIOPT Version :9

Sequence 1:	NP_001259908.1	Gene:	aop / 33392	FlyBaseID:	FBgn0000097	Length:	732	Species:	Drosophila melanogaster
Sequence 2:	NP_001285547.1	Gene:	Ets21C / 33229	FlyBaseID:	FBgn0005660	Length:	475	Species:	Drosophila melanogaster

Alignment Length:	470	Identity:	113/470 - (24%)
Similarity:	183/470 - (38%)	Gaps:	139/470 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   221 ATNTSNPTS-------SSASSTGSNGSQPNIMPMKGISSASS-NHSDSEEEYSETSGGV-SKMP- 275
            |..|..||:       .|:|||..             ||||| :.:||:...|.:|..: |::|
  Fly    53 AKETEVPTNRRRRRRRCSSSSTSD-------------SSASSYSSTDSDSGSSTSSSSIRSQLPA 104

  Fly   276 ---PAPLSYSTASPPG---------------------TPILKDIKPN-WTQQLTNSFVNSWSQQQ 315
               |.||..:|.:||.                     :|:...:.|: ||.:...|:|. |:
  Fly   105 LNLPVPLPLATPTPPAVSSPHQAPSPRRNSSDSNRSVSPVEVPVDPHAWTPEDIASWVR-WA--- 165

  Fly   316 QQQQQQQAAAVAAVAAQAQQHQLQQQQQQQQLP---QKL-TLDNT-----AGPVVTPAGGSISAP 371
                             .::.:|..:....:.|   |:| .|...     ||   :..||.:.|.
  Fly   166 -----------------TRKFKLDPEPDIDRFPKDAQELCDLSRADFWVCAG---SRRGGMLLAQ 210

  Fly   372 TTPSYMYKAK-REFFP--ENSEPN----------------TNGRL-LWDFLQQLLNDRNQKYSDL 416
            .....:|.|. ||..|  .:.|||                :.|:: ||.||.:||.|.:.  ::.
  Fly   211 HFAISLYHATGRETSPMLNDDEPNPYQLLNAASHRLVAQGSGGQIQLWQFLLELLADSSN--ANA 273

  Fly   417 IAWKCRDTGVFKIVDPAGLAKLWGIQKNHLSMNYDKMSRALRYYYRVNILRKVQGERHCYQFLRN 481
            |:|: ..:|.|:::||..:|:.||.:|...:|||||:||||||||..||:.||.|:|:.|:|
  Fly   274 ISWE-GQSGEFRLIDPDEVARRWGERKAKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF--- 334

  Fly   482 PTELKNIKNISLLRQSTPANGNGGSPSMPQ---------GSSQAPGSPAGQNWNPQQQSQQQQQS 537
                    :...|..:..|...||.|:...         |:.|....|...:.:||......|..
  Fly   335 --------DFHGLMAACQAQAQGGDPASSMLGSYNHHAGGAMQLGRHPPPLHHHPQHSHPHHQLG 391

  Fly   538 P--------QRPASRNGPMSLPAVAAVAAAAAAAYGPPPTSPLFMHAINGAFHYLSAAAAGPPPN 594
            .        ..|||.:..:..|:.:..::.|:....|..:|.       ...::.:....|....
  Fly   392 QPHFLHPHHSSPASNSSSLGFPSSSTASSQASPGQAPASSSA-------STSNFTAPFQGGTAGV 449

  Fly   595 SPALNTPSAVGGPDK 609
            .||..:.|:.|..|:
  Fly   450 DPARTSTSSAGNYDQ 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
aop	NP_001259908.1	SAM_PNT-Tel_Yan	49..116	CDD:176085
aop	NP_001259908.1	ETS	395..482	CDD:197710	39/87 (45%)
Ets21C	NP_001285547.1	SAM_PNT	149..217	CDD:188876	16/91 (18%)
Ets21C	NP_001285547.1	ETS	254..339	CDD:197710	38/98 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	87	1.000	Inparanoid score	I3709
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11849
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.060