DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment aop and AgaP_AGAP007327

DIOPT Version :9

Sequence 1:	NP_001259908.1	Gene:	aop / 33392	FlyBaseID:	FBgn0000097	Length:	732	Species:	Drosophila melanogaster
Sequence 2:	XP_564896.3	Gene:	AgaP_AGAP007327 / 3290353	VectorBaseID:	AGAP007327	Length:	763	Species:	Anopheles gambiae

Alignment Length:	536	Identity:	121/536 - (22%)
Similarity:	180/536 - (33%)	Gaps:	201/536 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 PNSPVTPTSRYPLSPHSHPPTPTWPPLNAPPENSPFHSSAHSLAGHHFMAPNSV---TLSPPPSV 186
            |:..:...:..|:.|.|  |:|       ||:      ...||||.......|:   ||.|
Mosquito   252 PDIVIKVDTEIPILPQS--PSP-------PPQ------QRSSLAGGQSQQTASLLASTLQP---- 297

  Fly   187 DSQASSP-----------PQAPYQNG---GATGAAP------------GSAGGSAPAA------- 218
             ||...|           ||.||..|   .:||:.|            .|:.|..||.
Mosquito   298 -SQQHRPLLHGLLSGTHLPQGPYHRGYSTSSTGSLPPSPADSGVSDVDSSSSGGQPACSDELKAR 361

  Fly   219 -GGATNTSNPTSSSAS--STGSNGSQPNIMPMKGISSASSNHSDSEEEYSETSGGVSKMPP--AP 278
             |..|:::.|.|:...  ||.|..::.....|.|.|:.|.:.|.:..:.:..:....:..|  .|
Mosquito   362 LGIPTSSTGPVSNQPGQPSTRSRVNRSRCTRMAGPSATSLSSSSALSQVAAAAAAHLQSGPFLRP 426

  Fly   279 LSYSTASPPGTPILKDIKPNWTQQ----------------------------------------- 302
            ..|..:|||    |::|   |.|:
Mosquito   427 NFYHHSSPP----LRNI---WNQRSYAPDTYYSVLRCGAMVPYCAGRNSPRKVAYQTIARIEEAA 484

  Fly   303 --LTNSFVN--SWSQQ-----QQQQQQQQAAAVAAVAAQAQQHQLQQQQQQ---QQLPQKLTLDN 355
              ..|:..|  :|..:     ..::|::...::.....:...|:...::.:   .:...:.|.|.
Mosquito   485 RCTRNASANARAWLAEISLRTTDEKQERNGRSIFMEQLERLLHETSAERAELATSETKSRTTHDK 549

  Fly   356 TA--GPVVTP---------------------------------AGG------------------- 366
            |.  |.:..|                                 .||
Mosquito   550 TTPHGHLAAPHHAGNPNGHHHGAHLGQQHGLGHHGHAGSGHVVGGGANSAAAAAAALMANGIGLG 614

  Fly   367 ----------SISAPTTPSYMY-------------KAKREFFPENSEPNTNGRLLWDFLQQLLND 408
                      |.|.|...|||.             |.|.|...:......:...||:||.:||.|
Mosquito   615 HHGQHGPHSVSSSCPDDLSYMLELGFQPRKLKKPKKPKLEMGVKRKSREGSTTYLWEFLLKLLQD 679

  Fly   409 RNQKYSD-LIAWKCRDTGVFKIVDPAGLAKLWGIQKNHLSMNYDKMSRALRYYYRVNILRKVQGE 472
            |  :|.. .|.|..||.||||:||...::||||:.||...|||:.|.|||||||:..||.||.|:
Mosquito   680 R--EYCPRFIKWTNRDKGVFKLVDSKAVSKLWGMHKNKPDMNYETMGRALRYYYQRGILAKVDGQ 742

  Fly   473 RHCYQFLRNPTELKNI 488
            |..|||:..|.::..|
Mosquito   743 RLVYQFVDVPKDIVEI 758

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
aop	NP_001259908.1	SAM_PNT-Tel_Yan	49..116	CDD:176085
aop	NP_001259908.1	ETS	395..482	CDD:197710	45/87 (52%)
AgaP_AGAP007327	XP_564896.3	HIP1_clath_bdg	31..100	CDD:293123
AgaP_AGAP007327	XP_564896.3	Ets	669..749	CDD:278602	44/81 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910