DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment aop and elf1

DIOPT Version :9

Sequence 1:	NP_001259908.1	Gene:	aop / 33392	FlyBaseID:	FBgn0000097	Length:	732	Species:	Drosophila melanogaster
Sequence 2:	NP_571234.2	Gene:	elf1 / 30396	ZFINID:	ZDB-GENE-980526-335	Length:	639	Species:	Danio rerio

Alignment Length:	572	Identity:	145/572 - (25%)
Similarity:	205/572 - (35%)	Gaps:	158/572 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   209 GSAGGS--APAAGGATNTSNPTSSSASSTGSNGSQPNIMPMKGISSASSNHSDSEEEYSETSGGV 271
            |..|.|  .|.:||..|.....::.|.                ::..|.|:...|:....|.|.:
Zfish    75 GDVGLSVETPVSGGEDNMETIEAAEAL----------------LNMESPNNILDEKRMIHTYGNI 123

  Fly   272 SKMPPAPLSYSTASPPGTPILKDIKPNWTQQLTNSFVNSWSQQQQQQQQQQAAAVAAVAAQAQQH 336
            .:   ..|||.:..|              :.|:|..                    .||...:..
Zfish   124 LE---TDLSYISLRP--------------EHLSNGM--------------------DVAHDDETS 151

  Fly   337 QLQQQQQQQQLPQKLTLDNTAGP-----VVTPAGGSISAP-TTPSYMYKAKREFFPENSEPNTNG 395
            .|      .::|||    |.:.|     |..|......:| |.||...|.|      :.|...|.
Zfish   152 SL------DEVPQK----NFSKPARKTKVRKPRPARPCSPITNPSLPLKKK------SKEGKGNT 200

  Fly   396 RLLWDFLQQLLNDRN--QKYSDLIAWKCRDTGVFKIVDPAGLAKLWGIQKNHLSMNYDKMSRALR 458
            ..||:||..||.|:|  .||   |.|..|:.|:||:||...::||||..||...|||:.|.||||
Zfish   201 IYLWEFLLALLQDKNTCPKY---IKWTQREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALR 262

  Fly   459 YYYRVNILRKVQGERHCYQFLRNPTELKNIKNISLLRQSTPANGNGGSPSMPQGSSQAPGSPAGQ 523
            |||:..||.||:|:|..|||...||:|..|...........| |.||..:.|.| ....||...|
Zfish   263 YYYQRGILAKVEGQRLVYQFKEMPTDLVIIDEDDGQGDDGGA-GYGGHRAAPHG-RVGRGSSRSQ 325

  Fly   524 NWNPQQQSQQQQQSPQRPASRNGPMS---LPAVAAVAAAAAAAYGPPPTSPLFMHAINGAFHYLS 585
            ..|.|.::.:::.||.. .||||..:   |..|..:.....||.      |...|::.
Zfish   326 GRNTQVKTVKREMSPGL-NSRNGKQAEQLLQTVHVLQPNQGAAV------PAQTHSVR------- 376

  Fly   586 AAAAGPPPNSPALNTPSAV-GGPDKFQFHPLK--LENGSGS--------------GSESAGEDLK 633
              ....|.:.|.:.|..|. |||...|..||.  |.||..|              .:...|:|:
Zfish   377 --TINMPGSVPMVLTSGAQGGGPMTLQTLPLSSVLTNGDSSTHASPPRVILHTVPSTSPGGKDV- 438

  Fly   634 PTDLSVSSKSTATSNEDCYPLI-------------------RNADGLTTIKLIRYNEHQVAASPA 679
               |::.:.|..|.:.....|:                   .:.:|:|.:..:..|...|.|
Zfish   439 ---LTIQTASLTTDSLHSQQLLVSTLSSSSGGVISTTPQQTASLNGITRLVTLNANGQPVVA--- 497

  Fly   680 GQSPKHDDQQAGASNAS----SSPRPMDQASEQAQPVPMESDCNGGESEDSF 727
                    ||.|...|:    |..:.:....|.:.|...:|..|...|..||
Zfish   498 --------QQPGTVIATVLKPSEYQSLQVKEEISDPQYFQSLVNNSPSFASF 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
aop	NP_001259908.1	SAM_PNT-Tel_Yan	49..116	CDD:176085
aop	NP_001259908.1	ETS	395..482	CDD:197710	44/88 (50%)
elf1	NP_571234.2	Elf-1_N	2..107	CDD:289109	8/47 (17%)
elf1	NP_571234.2	Ets	203..282	CDD:278602	42/81 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3804
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810