DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment aop and Elf4

DIOPT Version :9

Sequence 1:	NP_001259908.1	Gene:	aop / 33392	FlyBaseID:	FBgn0000097	Length:	732	Species:	Drosophila melanogaster
Sequence 2:	NP_001178664.1	Gene:	Elf4 / 302811	RGDID:	1560743	Length:	660	Species:	Rattus norvegicus

Alignment Length:	491	Identity:	119/491 - (24%)
Similarity:	189/491 - (38%)	Gaps:	105/491 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 ASSNHSDSEEEYSETSGGVSKMPPAPLSYSTASPP---------GTP-ILKDIKPNWTQQLTNSF 307
            ::||:|.|.|                :.::.|:|.         .|| :|.|........|.| |
  Rat    86 STSNNSSSTE----------------VLFNVATPSDVLDEKQIFSTPEVLPDSNSVQAINLPN-F 133

  Fly   308 VNSWSQQQQQQQQQQAAAVAAVAAQAQQHQLQQQQQQQQLPQ--------KLTLDNTAGPVVTPA 364
            :.|..:....::...       |...:::.|::..:::.|.:        :.|.:|.
  Rat   134 LLSTPEPDDPKKTSD-------AGDQKEYSLEEVSREENLRKIGKSRKRNRKTKNNR-------- 183

  Fly   365 GGSISAPTTPSYMYKAKREFFPENSEPNTNGR----LLWDFLQQLLNDRN--QKYSDLIAWKCRD 423
              |.|..|.||...:.|          :.:|:    .||:||..||.|||  .||   |.|..|:
  Rat   184 --STSPVTDPSVPIRKK----------SKDGKGSTIYLWEFLLALLQDRNTCPKY---IKWTQRE 233

  Fly   424 TGVFKIVDPAGLAKLWGIQKNHLSMNYDKMSRALRYYYRVNILRKVQGERHCYQFLRNPTELKNI 488
            .|:||:||...::||||.|||...|||:.|.|||||||:..||.||:|:|..|||...|.:|..|
  Rat   234 KGIFKLVDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLVVI 298

  Fly   489 KNISLLRQSTPANGNGGSPSMPQGS-SQAPGSPAGQNWNPQQQSQQQQQSPQRPASRNGPMSLPA 552
            .:.....::...:....:.|.|..| ::.|.|......:|:.:.....:.|:  ....|   |..
  Rat   299 DDEEESTETPEDSSQASTSSTPSTSTTRRPSSRVVTRASPEDKDSPSWEKPK--VEHTG---LQP 358

  Fly   553 VAAVAAAAAAAYGPPPTSPLFMHAINGAFHYLSAAAAGPPPNSPALNTPSAVGGPDKFQFHPLK- 616
            .|::....:.....|.||.:.:..:..........:...|.|......|...|.....|..||.
  Rat   359 SASLELGLSVDEEVPTTSTMIVSPLQSQAKPAKTVSTSAPSNIHLGVAPVGPGSTVTLQTIPLTT 423

  Fly   617 -LENGSGSGSESAGEDLKPTDLSVSSKSTATSNEDCYPLIRNADGLTTIKLIRYNEHQVA----- 675
             |.||..:|:.:..:.:..:...||:.....:.:..:||  ||.         ..|:|||
  Rat   424 VLTNGPPAGTTAPAQLVLQSVPQVSTFKDTLTLQTSFPL--NAS---------LQENQVATQGTP 477

  Fly   676 ----------ASPAGQSPKHDDQQAGASNASSSPRP 701
                      |....||.....|..||.:|..|.:|
  Rat   478 LILSGLPQLLAGANHQSNPVTSQVIGAGSAGPSSQP 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
aop	NP_001259908.1	SAM_PNT-Tel_Yan	49..116	CDD:176085
aop	NP_001259908.1	ETS	395..482	CDD:197710	47/92 (51%)
Elf4	NP_001178664.1	Elf-1_N	2..103	CDD:403506	6/32 (19%)
Elf4	NP_001178664.1	Ets	208..288	CDD:395126	44/82 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3804
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810