DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment aop and Fev

DIOPT Version :9

Sequence 1:	NP_001259908.1	Gene:	aop / 33392	FlyBaseID:	FBgn0000097	Length:	732	Species:	Drosophila melanogaster
Sequence 2:	NP_653354.2	Gene:	Fev / 246271	RGDID:	628860	Length:	237	Species:	Rattus norvegicus

Alignment Length:	287	Identity:	80/287 - (27%)
Similarity:	124/287 - (43%)	Gaps:	71/287 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   338 LQQQQQQQQLPQKLTLDNTAGPVVTPAGGSIS-APTTPSYMYKAKREFFPENSEPNTNGRL-LWD 400
            ::|....|.|...:.|.:..|..:...|.|.| .|.:|:..              ..:|:: ||.
  Rat     1 MRQSGTSQPLLINMYLPDPVGDGLFKEGKSPSWGPLSPAVQ--------------KGSGQIQLWQ 51

  Fly   401 FLQQLLNDRNQKYSDLIAWKCRDTGVFKIVDPAGLAKLWGIQKNHLSMNYDKMSRALRYYYRVNI 465
            ||.:||.||..  :..|||: ...|.||:.||..:|:.||.:|:..:|||||:||||||||..||
  Rat    52 FLLELLADRAN--AGCIAWE-GGHGEFKLTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNI 113

  Fly   466 LRKVQGERHCYQFLRNPTELKNIKNISLLRQSTPANGNGGSPSMPQGSSQAPGS----PAGQNWN 526
            :.||.|:|:.|:|        :.:.::...|..||:.:..:.:....::...|:    |||
  Rat   114 MSKVHGKRYAYRF--------DFQGLAQACQPPPAHAHAAAAAAAAAAAAQDGALYKLPAG---- 166

  Fly   527 PQQQSQQQQQSPQRPASRNGPMSLPAVAAVAAAAAAAYGPPPTSPLFMHAINGAFHYLSAAAAG- 590
                     .:| .|......::|.|.:|..|.|..:|.|.|.:              :||||.
  Rat   167 ---------LAP-LPFPGLSKLNLMAASAGVAPAGFSYWPGPNA--------------TAAAAAT 207

  Fly   591 ----------PPPNS-PALNTPSAVGG 606
                      |||.. .|:...|.:||
  Rat   208 AALYPTPGLQPPPGPFGAVAAASHLGG 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
aop	NP_001259908.1	SAM_PNT-Tel_Yan	49..116	CDD:176085
aop	NP_001259908.1	ETS	395..482	CDD:197710	42/87 (48%)
Fev	NP_653354.2	ETS	46..131	CDD:197710	41/95 (43%)
Fev	NP_653354.2	May mediate active transcriptional repression. /evidence=ECO:0000250	129..237		28/134 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910