Protein Alignment aop and ETV4

DIOPT Version :9

• Sequence 1: NP_001259908.1
• Gene: aop / 33392
• FlyBaseID: FBgn0000097
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_001073143.1
• Gene: ETV4 / 2118
• HGNCID: 3493
• Length: 484
• Species: Homo sapiens
• Alignment Length: 563
• Identity: 135/563 - (23%)
• Similarity: 189/563 - (33%)
• Gaps: 197/563 - (34%)

  Fly    72 LPKLDF-DLFQMNGKALCLLTRADFGH---------RCPGAGDVLHNVLQMLIIESHMMQWHLPN 126
            ||.||. ||||            |..|         :.|.:.            |..:..:|..|
Human    45 LPPLDSEDLFQ------------DLSHFQETWLAEAQVPDSD------------EQFVPDFHSEN 85

  Fly   127 ----SPVTPTSRYPLSPHSHP--PTPTWPPLNAPPENSPFHSSAHSLAGHHFMAPNSVTLSPPPS 185
                ||.|...:.|.||.:.|  .....|||       |:|.....|....:..|..:.:..|
Human    86 LAFHSPTTRIKKEPQSPRTDPALSCSRKPPL-------PYHHGEQCLYSSAYDPPRQIAIKSP-- 141

  Fly   186 VDSQASSPPQAPYQNGGATGAAPGSAGGSAPAAGGATNTSNPTSSSASSTGSNGSQPNIMPMKGI 250
                                 |||:.|.|...........|...||.:      |||:  |..|.
Human   142 ---------------------APGALGQSPLQPFPRAEQRNFLRSSGT------SQPH--PGHGY 177

  Fly   251 SSASSNHSDSEEE-----YSETSGGVSKMP-PAPLSYSTASPPGTPILKDIKPNWTQQLTNSFVN 309
               ...||...::     :|.||.|..:.| |||..:..:.|         .|.:.||
Human   178 ---LGEHSSVFQQPLDICHSFTSQGGGREPLPAPYQHQLSEP---------CPPYPQQ------- 223

  Fly   310 SWSQQQQQQQQQQAAAVAAVAAQAQQHQ-------LQQQQQQQQLPQKLT--------LDNTAGP 359
            |:.|:......:||...|........|:       ::|:|........:|        .:..:||
Human   224 SFKQEYHDPLYEQAGQPAVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGP 288

  Fly   360 VVTPAGGSISAPTTPSYMY-KAKREF----------------------FPENSEPNTNGRL-LWD 400
              :|..|::      .|.| |..|.|                      |.|.......|.| ||.
Human   289 --SPGDGAM------GYGYEKPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQ 345

  Fly   401 FLQQLLNDRNQKYSDLIAWKCRDTGV-FKIVDPAGLAKLWGIQKNHLSMNYDKMSRALRYYYRVN 464
            ||..||:|....:  .|||..|  |: ||:::|..:|:|||||||..:|||||:||:|||||...
Human   346 FLVALLDDPTNAH--FIAWTGR--GMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKG 406

  Fly   465 ILRKVQGERHCYQFLRNPTELKNIKNISLLRQSTPANGNGGSPSMPQGSSQAPGSPAGQNWNPQQ 529
            |::||.|||:.|:|:..|..|.::.                                    .|..
Human   407 IMQKVAGERYVYKFVCEPEALFSLA------------------------------------FPDN 435

  Fly   530 QSQQQQQSPQRPASRNGPMSL------PAVAAVAAAAAAAYGP 566
            |....:....||.|....:.|      ||.....|..|..:||
Human   436 QRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGP 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aop	NP_001259908.1	SAM_PNT-Tel_Yan	49..116	CDD:176085	11/53 (21%)
		ETS	395..482	CDD:197710	45/88 (51%)
ETV4	NP_001073143.1	ETS_PEA3_N	8..339	CDD:309665	76/382 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	90..115		7/24 (29%)
		ETS	341..424	CDD:197710	44/86 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910