Protein Alignment aop and ELF3

DIOPT Version :10

• Sequence 1: NP_523455.2
• Gene: aop / 33392
• FlyBaseID: FBgn0000097
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_004424.3
• Gene: ELF3 / 1999
• HGNCID: 3318
• Length: 371
• Species: Homo sapiens
• Alignment Length: 497
• Identity: 111/497 - (22%)
• Similarity: 174/497 - (35%)
• Gaps: 203/497 - (40%)

  Fly    29 PPA------------PSSQLAELKTQLPPSLPSDPRLWSREDVLVFLRFCV--REFDLPKLDFDL 79
            |||            .:.|::...|:....|...|:.||:..||.::.:.|  .::|...:||..
Human    30 PPAATFGADDLVLTLSNPQMSLEGTEKASWLGEQPQFWSKTQVLDWISYQVEKNKYDASAIDFSR 94

  Fly    80 FQMNGKALCLLT----RADFGHRCPGAGDVLHNVLQMLIIESHMMQWHLPNSPVTPTSRYPLSPH 140
            ..|:|..||...    |..||    ..||.||..|:.|                |.:|...||
Human    95 CDMDGATLCNCALEELRLVFG----PLGDQLHAQLRDL----------------TSSSSDELS-- 137

  Fly   141 SHPPTPTW-------------PPLNAPP--ENSPFHSSAHSLAGHHFMAPNSVTLSPPPSVDSQA 190
                   |             ..|:..|  :.|||   |..|..                 |.|.
Human   138 -------WIIELLEKDGMAFQEALDPGPFDQGSPF---AQELLD-----------------DGQQ 175

  Fly   191 SSPPQAPYQNGGATGAAPGSAGGSAPAAGGATNTSNPTSSSASSTGSNGSQPNIMPMKGISSASS 255
            :|    ||.        |||.|..||         :|.||..|:.|:..|:         ||.||
Human   176 AS----PYH--------PGSCGAGAP---------SPGSSDVSTAGTGASR---------SSHSS 210

  Fly   256 NHSDSEEEYSETSGGVSKMPPAPLSYSTASPPGTPILKDIKPNWTQQLTNSFVNSWSQQQQQQQQ 320
            :...|:.:...|.|   |:.|:         .|   .:|.|
Human   211 DSGGSDVDLDPTDG---KLFPS---------DG---FRDCK------------------------ 236

  Fly   321 QQAAAVAAVAAQAQQHQLQQQQQQQQLPQKLTLDNTAGPVVTPAGGSISAPTTPSYMYKAKREFF 385
                          :...:..::::..|:||:                             :|::
Human   237 --------------KGDPKHGKRKRGRPRKLS-----------------------------KEYW 258

  Fly   386 P----ENSEPNTNGRLLWDFLQQLL--NDRNQKYSDLIAWKCRDTGVFKIVDPAGLAKLWGIQKN 444
            .    :.|:....|..||:|::.:|  .:.|:   .|:.|:.|..||||.:....:|:|||.:|.
Human   259 DCLEGKKSKHAPRGTHLWEFIRDILIHPELNE---GLMKWENRHEGVFKFLRSEAVAQLWGQKKK 320

  Fly   445 HLSMNYDKMSRALRYYYRVNILRKVQGERHCYQFLRNPTELK 486
            :.:|.|:|:|||:||||:..||.:|.|.|..|:|.:|.:..|
Human   321 NSNMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSGWK 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aop	NP_523455.2	SAM_PNT-Tel_Yan	49..116	CDD:176085	22/72 (31%)
		ETS	395..482	CDD:197710	35/88 (40%)
ELF3	NP_004424.3	SAM_PNT-ESE-1-like	53..132	CDD:188880	25/98 (26%)
		9aaTAD	137..145		2/16 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	173..251		28/160 (18%)
		ETS	272..359	CDD:197710	36/89 (40%)