Protein Alignment aop and ELF2

DIOPT Version :9

• Sequence 1: NP_001259908.1
• Gene: aop / 33392
• FlyBaseID: FBgn0000097
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_001317965.1
• Gene: ELF2 / 1998
• HGNCID: 3317
• Length: 593
• Species: Homo sapiens
• Alignment Length: 650
• Identity: 140/650 - (21%)
• Similarity: 225/650 - (34%)
• Gaps: 225/650 - (34%)

  Fly   228 TSSSASSTGSNGSQPNIMPMKGISSASSNHSDSEEEYSETSGG----VSKMPPAPLSYSTAS--- 285
            ||:...|.|:            |...|||..:::||..:.|..    |..:|.|.|....|:
Human     2 TSAVVDSGGT------------ILELSSNGVENQEESEKVSEYPAVIVEPVPSARLEQGYAAQVL 54

  Fly   286 --PPGTPILKDIKPNWTQQLTNSFVNSWSQQQQQQQQQQAAAVAAVAAQAQQH----QLQQQQQQ 344
              ...|.:::|:                 .::|:.:.:....|.|....:..|    .::..:..
Human    55 VYDDETYMMQDV-----------------AEEQEVETENVETVEASVHSSNAHCTDKTIEAAEAL 102

  Fly   345 QQLPQKLTLDNTAGPV---VTPAGGSISAPTTPSYMYKAKR---------EFFPENSEP------ 391
            ..:.....|.::..||   |.|      ..:||.:::.|.|         |...|.|||
Human   103 LHMESPTCLRDSRSPVEVFVPP------CVSTPEFIHAAMRPDVITETVVEVSTEESEPMDTSPI 161

  Fly   392 ------------------------------------------NTNGRLLWDFLQQLLNDRN--QK 412
                                                      ..|...||:||..||.|:|  .:
Human   162 PTSPDSHEPMKKKKVGRKPKTQQSPISNGSPELGIKKKPREGKGNTTYLWEFLLDLLQDKNTCPR 226

  Fly   413 YSDLIAWKCRDTGVFKIVDPAGLAKLWGIQKNHLSMNYDKMSRALRYYYRVNILRKVQGERHCYQ 477
            |   |.|..|:.|:||:||...::||||..||...|||:.|.|||||||:..||.||:|:|..||
Human   227 Y---IKWTQREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQ 288

  Fly   478 F---------------------LRNPTELKNIKNISLLRQSTPANGNGGSPSMPQGSSQAPGSPA 521
            |                     |...|:.|:::.:||..:|.              ...|....:
Human   289 FKDMPKNIVVIDDDKSETCNEDLAGTTDEKSLERVSLSAESL--------------LKAASSVRS 339

  Fly   522 GQNWNPQQQSQQQQ--------QSPQRPASRNGPMSLPAVAAVAAAAAAAYGPPPT------SPL 572
            |:|.:|...|:.::        .||...||...|.:..:|:|.||        |.|      .|:
Human   340 GKNSSPINCSRAEKGVARVVNITSPGHDASSRSPTTTASVSATAA--------PRTVRVAMQVPV 396

  Fly   573 FMHAINGAFHYLSAAA--AGPP---PNSPALNT-------------PSAVGGPDKFQFHPLKL-- 617
            .|.::......::..:  ||.|   ..||...|             |::....||....|.|:
Human   397 VMTSLGQKISTVAVQSVNAGAPLITSTSPTTATSPKVVIQTIPTVMPASTENGDKITMQPAKIIT 461

  Fly   618 --------------ENGSGSGSESAGEDLKPTDLSVSSKSTATSNEDCYPLIR------NADGLT 662
                          .|.:||||    .::..|.|:|.: .|..|.....|::|      .|.|.|
Human   462 IPATQLAQCQLQTKSNLTGSGS----INIVGTPLAVRA-LTPVSIAHGTPVMRLSMPTQQASGQT 521

  Fly   663 TIKLIR--YNEHQVAASPAGQSPKHD--------DQQAGASNASSSPRPMDQASEQAQPVPMESD 717
            ..::|.  ....:|.:....:..:||        ::.|..:...:....:...|..|.||.|:::
Human   522 PPRVISAVIKGPEVKSEAVAKKQEHDVKTLQLVEEKPADGNKTVTHVVVVSAPSAIALPVTMKTE 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aop	NP_001259908.1	SAM_PNT-Tel_Yan	49..116	CDD:176085
		ETS	395..482	CDD:197710	44/109 (40%)
ELF2	NP_001317965.1	Elf-1_N	3..108	CDD:315071	21/133 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	146..201		5/54 (9%)
		ETS	207..289	CDD:197710	41/84 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3804
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810