Protein Alignment aop and ELF1

DIOPT Version :9

• Sequence 1: NP_001259908.1
• Gene: aop / 33392
• FlyBaseID: FBgn0000097
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_001357259.1
• Gene: ELF1 / 1997
• HGNCID: 3316
• Length: 619
• Species: Homo sapiens
• Alignment Length: 565
• Identity: 131/565 - (23%)
• Similarity: 207/565 - (36%)
• Gaps: 158/565 - (27%)

  Fly   246 PMKGISSASSNHSDSEEEYSETSGGVSKMPPAPLSYSTASPPGTPILKDIKPNWTQQLTNSFVNS 310
            ||......::|...|.|:         .|..||:::.:.:..|.|.:.:     |||:...:.:|
Human   113 PMLDEKRINNNIFSSPED---------DMVVAPVTHVSVTLDGIPEVME-----TQQVQEKYADS 163

  Fly   311 WSQQQQQQQQQQAAAVAAVAAQAQQHQLQQQQQQQQLPQKLTLDNTAGPVVTPAGGSISAPTTPS 375
            ......:|.:::                :.::.:...|.            :||       |||:
Human   164 PGASSPEQPKRK----------------KGRKTKPPRPD------------SPA-------TTPN 193

  Fly   376 YMYKAKREFFPENSEPNTNGRLLWDFLQQLLNDRN--QKYSDLIAWKCRDTGVFKIVDPAGLAKL 438
            ...|.|      |.:...|...||:||..||.|:.  .||   |.|..|:.|:||:||...:::|
Human   194 ISVKKK------NKDGKGNTIYLWEFLLALLQDKATCPKY---IKWTQREKGIFKLVDSKAVSRL 249

  Fly   439 WGIQKNHLSMNYDKMSRALRYYYRVNILRKVQGERHCYQFLRNPTELKNIKN---ISLLRQSTPA 500
            ||..||...|||:.|.|||||||:..||.||:|:|..|||...|.:|..|.:   .|.:..|.|:
Human   250 WGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYINDEDPSSSIESSDPS 314

  Fly   501 NGNGGSPSMPQGS----SQAPG-------------SPAGQNWNPQQQSQ--------QQQQS--- 537
            ..:..:.:..|.|    |.:||             |.|.:..:|.:.:|        |..||
Human   315 LSSSATSNRNQTSRSRVSSSPGVKGGATTVLKPGNSKAAKPKDPVEVAQPSEVLRTVQPTQSPYP 379

  Fly   538 ----------------PQRPASRNGPM-------SLPAVAAVAAAAAAAYGPPPTSPLFMHAING 579
                            |:..|:|...|       |:.::..:.|        |...|:.:...|.
Human   380 TQLFRTVHVVQPVQAVPEGEAARTSTMQDETLNSSVQSIRTIQA--------PTQVPVVVSPRNQ 436

  Fly   580 AFHYLSAAAAGPPPNSPALNTPSAVGGPDKFQFHPLK-------LENGSGSGSESAGED----LK 633
            ..|.::.... |.....|...|||..|..||....:.       |:......|:.||..    |.
Human   437 QLHTVTLQTV-PLTTVIASTDPSAGTGSQKFILQAIPSSQPMTVLKENVMLQSQKAGSPPSIVLG 500

  Fly   634 PTDLSVSSKSTATSNED--CYPLIRNADG---LTTIKLIRYN--EHQVAASPAG---------QS 682
            |..:    :...|||..  |...:..|..   ..|..::.::  ..|:.|.|.|         |.
Human   501 PAQV----QQVLTSNVQTICNGTVSVASSPSFSATAPVVTFSPRSSQLVAHPPGTVITSVIKTQE 561

  Fly   683 PKHDDQQAGASNASSSPRPMDQASEQAQPVP---MESDCNGGESE 724
            .|...|:.....:....:...:.:|| ||.|   :.|..||..|:
Human   562 TKTLTQEVEKKESEDHLKENTEKTEQ-QPQPYVMVVSSSNGFTSQ 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aop	NP_001259908.1	SAM_PNT-Tel_Yan	49..116	CDD:176085
		ETS	395..482	CDD:197710	42/88 (48%)
ELF1	NP_001357259.1	Elf-1_N	2..111	CDD:372034
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	158..199		9/75 (12%)
		ETS	207..289	CDD:197710	40/84 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	300..366		12/65 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	564..592		5/28 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3804
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810