DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment aop and elf-1

DIOPT Version :9

Sequence 1:	NP_001259908.1	Gene:	aop / 33392	FlyBaseID:	FBgn0000097	Length:	732	Species:	Drosophila melanogaster
Sequence 2:	NP_001021180.1	Gene:	elf-1 / 175226	WormBaseID:	WBGene00016029	Length:	420	Species:	Caenorhabditis elegans

Alignment Length:	446	Identity:	124/446 - (27%)
Similarity:	170/446 - (38%)	Gaps:	129/446 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 PTPTWPPLNAPPENSPFHSSAHSLAGHHFMAPNS------------------VTLSPPPSVDSQA 190
            |.|....|..|...||.:.|:.:::.......|:                  .|.|..|.::.
Worm     8 PRPEPLLLVLPTATSPLNISSSNISSKSSRINNNNDNENDEEDDGRDLDVEMKTESEWPRIER-- 70

  Fly   191 SSPPQAPYQNGGATGAAPGSAGGSAPAAGGATNTSNPTSSSA-----------SSTGSNGSQPNI 244
               |...|.:|...         ||||.........|||.|.           |||.|  .:|..
Worm    71 ---PTPKYADGRRI---------SAPAVLAHGLFEIPTSCSVQITVLQQLLDQSSTLS--LEPTN 121

  Fly   245 MPMKGISSASSNHSDSEEEYSETSGGVSK---MPPAPLSYSTASPPGTPILKDIKPNWTQQL--T 304
            .|..|:.      :||..|.|.:|....:   .||.|    ...||..|:     |..|||:  .
Worm   122 SPDSGVG------TDSTPETSPSSSTTRRHAFAPPPP----RPRPPTVPL-----PTVTQQIPWQ 171

  Fly   305 NSFVNSWSQQQQQ-------QQQQQAAAVAAVAAQAQQHQLQ----QQQQQQQLPQKLTLDNTAG 358
            .|.:..|.||.|.       |:..|:|.:....:.:..:.|.    ..|.|...||.|.   ||.
Worm   172 TSTIWPWIQQAQSASTADATQRWLQSALLCPTTSASHPNLLTIPQISVQPQPTAPQTLL---TAA 233

  Fly   359 P-----VVTPAGGSISAPTTPS-------YMYKAKREFFPENSEPN-------TNGR-------- 396
            |     |.||..|.:....|||       |:....|.|    ||||       |.|:
Worm   234 PFISSTVFTPTCGDLLTTCTPSNPSLLHPYLLDTSRRF----SEPNPAPLAQRTPGKKQKDGQVT 294

  Fly   397 LLWDFLQQLLNDRNQKYS-DLIAWKCRDTGVFKIVDPAGLAKLWGIQKNHLSMNYDKMSRALRYY 460
            .||:||.:||.|  .:|| ..|.|..:..|:||:||...:::|||:.||...|||:.|.||||||
Worm   295 YLWEFLLRLLQD--DQYSPKFIKWIDQAKGIFKLVDSKAVSRLWGMHKNKPGMNYETMGRALRYY 357

  Fly   461 YRVNILRKVQGERHCYQFLRNPTELKN----------------IKNISLLRQSTPA 500
            |:..||:||.|:|..|:|:..|:::.:                |..|||.....||
Worm   358 YQRGILQKVDGQRLVYRFVHLPSDVASECDSSCESADSCDSPKISPISLKLMLQPA 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
aop	NP_001259908.1	SAM_PNT-Tel_Yan	49..116	CDD:176085
aop	NP_001259908.1	ETS	395..482	CDD:197710	41/95 (43%)
elf-1	NP_001021180.1	ETS	294..380	CDD:197710	40/87 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	87	1.000	Inparanoid score	I3709
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.960