Protein Alignment AIF and hcaD

DIOPT Version :10

• Sequence 1: NP_722765.2
• Gene: AIF / 33390
• FlyBaseID: FBgn0031392
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: NP_417037.1
• Gene: hcaD / 945427
• ECOCYCID: G7336
• Length: 400
• Species: Escherichia coli
• Alignment Length: 486
• Identity: 116/486 - (23%)
• Similarity: 185/486 - (38%)
• Gaps: 102/486 - (20%)

  Fly   253 KHVPYLIIGGGTAAFSAFRAIKSNDATAKVLMISNEFRKPYMRPPLSKELWYTPNPNEDPIKDYR 317
            |....:|:|||.||..|..:::....|.::.:.|:|...||.||||||.:....:|....:....
E. coli     2 KEKTIIIVGGGQAAAMAAASLRQQGFTGELHLFSDERHLPYERPPLSKSMLLEDSPQLQQVLPAN 66

  Fly   318 FKQWTGSERSLFFEPDEFFIDPEDLDDNANGGIAVAQGFSVKKVDAQKRIVTLNDGYEISYDECL 382
            :.|                          ...:.:..|.::|.:....|.:.|.:|....:|:..
E. coli    67 WWQ--------------------------ENNVHLHSGVTIKTLGRDTRELVLTNGESWHWDQLF 105

  Fly   383 IATGCAPKNLPMLRDAPPSVLEKVMVYRTPDDFDRLRKLAAEKRSITIVGNGFIGSELACSLAHY 447
            ||||.|.:.||:| ||   :.|:....|...|..|||::...:||:.|:|.|.||.|||.|..
E. coli   106 IATGAAARPLPLL-DA---LGERCFTLRHAGDAARLREVLQPERSVVIIGAGTIGLELAASAT-- 164

  Fly   448 SRENNGGKVYQVFQENANMSKVLPNYLSRWTTAKMEAQGVCVIPNASIRSAVRDETNLKLELNNG 512
               ....||..:......|.:..|..:.|:...:.:..||.::.|.:|...| |...::|.|.:|
E. coli   165 ---QRRCKVTVIELAATVMGRNAPPPVQRYLLQRHQQAGVRILLNNAIEHVV-DGEKVELTLQSG 225

  Fly   513 MTLMSDVVVVCVGCTPNTDLAGPSRLEVDRSLGGFVVNAELEARRN----LYVAGDASCFFDPLL 573
            .||.:|||:..:|.:.|..||..:.|:   :..|.|::   ||.|.    ::..||.:.......
E. coli   226 ETLQADVVIYGIGISANEQLAREANLD---TANGIVID---EACRTCDPAIFAGGDVAITRLDNG 284

  Fly   574 GRRRVEHHDHSVVSGRLAGENMTGAKKPYQHQSMFWSDLGPEIGYEGIGLVDSSLPTVGVFALPS 638
            ...|.|..:::....::|...|.|...|......||||           ....:|..:|
E. coli   285 ALHRCESWENANNQAQIAAAAMLGLPLPLLPPPWFWSD-----------QYSDNLQFIG------ 332

  Fly   639 ESATRVDQLSESSDSDVPETSTSSSQSSKSDAGASQDGVTCDPDEAGNYGKGVIFYLKNDKIVGI 703
             .....|.|...:    |||.                             |.:.|.|:|..::|.
E. coli   333 -DMRGDDWLCRGN----PETQ-----------------------------KAIWFNLQNGVLIGA 363

  Fly   704 LLWNLFNRIGLARTIINQNKKYDDLNEVAKL 734
            :..|....|...|..|...|.:|     |||
E. coli   364 VTLNQGREIRPIRKWIQSGKTFD-----AKL 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AIF	NP_722765.2	NirB	256..719	CDD:440863	109/466 (23%)
		AIF_C	591..721	CDD:464279	24/129 (19%)
hcaD	NP_417037.1	PRK09754	1..396	CDD:170080	116/486 (24%)