DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AIF and TRR1

DIOPT Version :9

Sequence 1:	NP_722765.2	Gene:	AIF / 33390	FlyBaseID:	FBgn0031392	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_010640.1	Gene:	TRR1 / 851955	SGDID:	S000002761	Length:	319	Species:	Saccharomyces cerevisiae

Alignment Length:	259	Identity:	54/259 - (20%)
Similarity:	91/259 - (35%)	Gaps:	79/259 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   318 FKQWTGSERSLFFEPDEFFIDPEDLDDNANGGIAVAQGFSVKKVDAQKRIVTLNDGYEISYDECL 382
            ||.||           ||..|.|.:..:|   |.:|.|.|.|::..        .|.|..:.:.:
Yeast    97 FKLWT-----------EFNEDAEPVTTDA---IILATGASAKRMHL--------PGEETYWQKGI 139

  Fly   383 IATGCAPKNLPMLRDAPPSVLEKVMVYRTPDDFDRLRKLAAEKRSITIVGNGFIGSELACSLAHY 447
            .|.......:|:.|:.|                            :.::|.|....|.|..|..|
Yeast   140 SACAVCDGAVPIFRNKP----------------------------LAVIGGGDSACEEAQFLTKY 176

  Fly   448 SRENNGGKVYQ-VFQENANMSKVLPNYLSR-------WTTAKMEAQGVCVIPNASIRSAVRDETN 504
                 |.||:. |.:::...|.::.....:       :.|..:||:|     :..:.:|:|.:..
Yeast   177 -----GSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKG-----DGKLLNALRIKNT 231

  Fly   505 LKLELNNGMTLMSDVVVVCVGCTPNTDL-AGPSRLEVDRSLGGF---VVNAELEARRNLYVAGD 564
            .|   |....|....:...:|.||.|.: ||    :||....|:   |..:.|.:....:.|||
Yeast   232 KK---NEETDLPVSGLFYAIGHTPATKIVAG----QVDTDEAGYIKTVPGSSLTSVPGFFAAGD 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AIF	NP_722765.2	Pyr_redox_2	257..573	CDD:285266	54/259 (21%)
		Pyr_redox	427..512	CDD:278498	19/92 (21%)
		AIF_C	591..720	CDD:291391
TRR1	NP_010640.1	TRX_reduct	5..315	CDD:273540	54/259 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345482
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840