Protein Alignment AIF and Aifm2

DIOPT Version :10

• Sequence 1: NP_722765.2
• Gene: AIF / 33390
• FlyBaseID: FBgn0031392
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: NP_722474.2
• Gene: Aifm2 / 71361
• MGIID: 1918611
• Length: 380
• Species: Mus musculus
• Alignment Length: 359
• Identity: 70/359 - (19%)
• Similarity: 131/359 - (36%)
• Gaps: 69/359 - (19%)

  Fly   254 HVPYLIIGGGTAAFSAFRAIKSNDATAKVLMISNEFRKPYMRPPLSKELWYTPNPNEDPIKDYRF 318
            ||  :|:|||....:|...:::             ...|:|...:.....:.       :...|.
Mouse    13 HV--VIVGGGFGGIAAASQLQA-------------LNVPFMLVDMKDSFHHN-------VAALRA 55

  Fly   319 KQWTGSERSLFFEPDEFFIDPEDLDDNANGGIAVAQGFSVKKVDAQKRIVTLNDGYEISYDECLI 383
            ...:|..:..|......|      .||...|..:.       :|.:.|:|.|..|..:.:...::
Mouse    56 SVESGFAKKTFISYSATF------KDNFRQGKVIG-------IDLKNRMVLLQGGEALPFSHLIL 107

  Fly   384 ATGCAPKNLPMLRDAP-PSVLEKVMVYRTP-DDFDRLRKLAAEKRSITIVGNGFIGSELACSLAH 446
            |||..         .| |....:|...:.. ..::.:.|.....:.|.:||.|..|.|:|   |.
Mouse   108 ATGST---------GPFPGKFNEVSCQQAAIQAYEDMVKQIQRSQFIVVVGGGSAGVEMA---AE 160

  Fly   447 YSRENNGGKVYQVFQENANMSKVLPNYLSRWTTAKMEAQGVCVIPN---ASIRSAVRDETN--LK 506
            ...|....:|..:........|.|...:.:.....:..:||.::.:   :::....|:|..  :|
Mouse   161 IKTEYPEKEVTLIHSRVPLADKELLPCVRQEVKEILLRKGVQLLLSERVSNLEELPRNEYREYIK 225

  Fly   507 LELNNGMTLMSDVVVVCVGCTPNTDL---AGPSRLEVDRSLGGFVVN--AELEARRNLYVAGDAS 566
            :|.:.|..:.:::|:||.|...|:..   |..|||   .|.|...||  .::|...|:|..||.:
Mouse   226 VETDKGTEVATNMVIVCNGIKINSSAYRSAFESRL---ASNGALKVNEFLQVEGYSNIYAIGDCA 287

  Fly   567 CFFDPLLGRRRVEHHDHSVVSGRLAGENMTGAKK 600
            ...:|.:..       |:.:...:|..|:..:.|
Mouse   288 DTKEPKMAY-------HAGLHANVAVANIVNSMK 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AIF	NP_722765.2	NirB	256..719	CDD:440863	68/357 (19%)
		AIF_C	591..721	CDD:464279	3/10 (30%)
Aifm2	NP_722474.2	Ndh	67..323	CDD:440864	58/283 (20%)