Protein Alignment AIF and Trxr-2

DIOPT Version :9

• Sequence 1: NP_722765.2
• Gene: AIF / 33390
• FlyBaseID: FBgn0031392
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: NP_524216.1
• Gene: Trxr-2 / 40475
• FlyBaseID: FBgn0037170
• Length: 516
• Species: Drosophila melanogaster
• Alignment Length: 555
• Identity: 108/555 - (19%)
• Similarity: 190/555 - (34%)
• Gaps: 165/555 - (29%)

  Fly   241 LATSPPSSE-DLPKHVPYLIIGGGTAAFSAFRAIKSNDATAKVLMISNEFRKPYMRPP------- 297
            ||.|.|..: ||      :::|||:|..:.  |.::....|:||...      |::|.
  Fly    24 LAASRPRYDYDL------VVLGGGSAGLAC--AKEAAGCGARVLCFD------YVKPTPVGTKWG 74

  Fly   298 ----------LSKELWYTPNPNEDPIKDYRFKQWTGSERSLFFEPD--------------EFFID 338
                      :.|:|.:..:...:.:.:.....|...:.::  .||              ..::.
  Fly    75 IGGTCVNVGCIPKKLMHQASLLGEAVHEAVAYGWNVDDTNI--RPDWRKLVRSVQNHIKSVNWVT 137

  Fly   339 PEDLDDNANGGIAVAQGFSVKKVDAQKRIVTLNDGYEISY-------------DECLIATGCAPK 390
            ..||.|              |||:....:.|..|.:.|.|             :..::|.|..|:
  Fly   138 RVDLRD--------------KKVEYVNSMATFRDSHTIEYVAMPGAEHRQVTSEYVVVAVGGRPR 188

  Fly   391 NLPMLRDAPPSVLEKVMVYRTPDD---FDRLRKLAAEKRSITIVGNGFIGSELACSLAHYSRENN 452
            .        |.:...|.:..|.||   ::|      |.....:||.|::|.|.||.|.
  Fly   189 Y--------PDIPGAVELGITSDDIFSYER------EPGRTLVVGAGYVGLECACFLK------- 232

  Fly   453 GGKVYQ-VFQENANMSKVLPNYLSRWTTAKMEAQGV----CVIPNASIRSAVRDETNLKLELNNG 512
             |..|: .....:.:.:.....:|....|.|..:|:    ..||.|..|.|   :..|.:...|.
  Fly   233 -GLGYEPTVMVRSIVLRGFDRQMSELLAAMMTERGIPFLGTTIPKAVERQA---DGRLLVRYRNT 293

  Fly   513 MTLMS-----DVVVVCVGCTP-----NTDLAG----PSRLEVDRSLGGFVVNAELEARRNLYVAG 563
            .|.|.     |.|:..:|...     |.|.||    ..::.||.        ||..:..:::..|
  Fly   294 TTQMDGSDVFDTVLWAIGRKGLIEDLNLDAAGVKTHDDKIVVDA--------AEATSVPHIFAVG 350

  Fly   564 DASCFFDPLLGRRRVEHHDHSVVSGRLAGENMTGAKKPYQHQSMFWSDLGPEI----GYEGIGLV 624
            |.      :.|  |.|....:::||||....:.....    |.|.::|:...:    .|..:|:.
  Fly   351 DI------IYG--RPELTPVAILSGRLLARRLFAGST----QLMDYADVATTVFTPLEYSCVGMS 403

  Fly   625 DSSLPTVGVFALPSESATRVDQLS---ESSDSDVPETSTSSSQSSKSDAGASQD----GVTCDPD 682
            :.:       |:....|..::...   :.::..:|:.|..... .|:.|..|.|    |:.....
  Fly   404 EET-------AIELRGADNIEVFHGYYKPTEFFIPQKSVRHCY-LKAVAEVSGDQKILGLHYIGP 460

  Fly   683 EAGNYGKGVIFYLKNDKIVGILLWNLFNRIGLART 717
            .||...:|....||    .|:.:..|.|.:|:..|
  Fly   461 VAGEVIQGFAAALK----TGLTVKTLLNTVGIHPT 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AIF	NP_722765.2	Pyr_redox_2	257..573	CDD:285266	71/381 (19%)
		Pyr_redox	427..512	CDD:278498	20/89 (22%)
		AIF_C	591..720	CDD:291391	24/138 (17%)
Trxr-2	NP_524216.1	NADB_Rossmann	29..>68	CDD:304358	13/52 (25%)
		TGR	31..515	CDD:273624	104/548 (19%)
		NADB_Rossmann	<144..239	CDD:304358	27/116 (23%)
		Pyr_redox	214..288	CDD:278498	20/84 (24%)
		Pyr_redox_dim	388..497	CDD:280934	21/116 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464290
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840