Protein Alignment AIF and Aifm3

DIOPT Version :9

• Sequence 1: NP_722765.2
• Gene: AIF / 33390
• FlyBaseID: FBgn0031392
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: XP_008767097.1
• Gene: Aifm3 / 303786
• RGDID: 1306028
• Length: 608
• Species: Rattus norvegicus
• Alignment Length: 761
• Identity: 164/761 - (21%)
• Similarity: 255/761 - (33%)
• Gaps: 284/761 - (37%)

  Fly    73 CVTKPSTTPPVE-------------EYETAVEGAGVP-AYANAQFQAHSQSEPLFKVGFADVKSV 123
            |.:||.   |||             :.|.:..|.|.| .|.......|..:|
  Rat     4 CFSKPK---PVELKIEVVLPEKERGKEELSASGKGSPRGYQGNGTARHFHAE------------- 52

  Fly   124 CSAKDVLKSDSAKLSTSQPVLDSCKATSP--CEEFKRKRKETTCQPCD-EDGTAPGGGDGGDEEC 185
                       .:|.|.||.      .||  |.|      .|.|...| |:|
  Rat    53 -----------ERLPTPQPY------PSPQDCVE------ATVCHVKDLENG------------- 81

  Fly   186 ECRMKDLRL---KCLL----GALAAL----------LAGGFLA-------W------FMTRDTDD 220
              :|:::.|   |.||    |...||          |..|.|:       |      ..|.|.:|
  Rat    82 --QMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNIGTGDLED 144

  Fly   221 -------------SEAKKA------EAEEEERKRRLVAGLATSPPSSEDLPKHVPYLIIGGGTAA 266
                         .|.:|.      :|.:.:|:.:::|...:  ||:.....:|  ||:|.|.|.
  Rat   145 FPGLDSLHKFQVKIEKEKVTVRASKQALQLQRRTKVMAKCIS--PSAGHSSTNV--LIVGAGAAG 205

  Fly   267 FSAFRAIKSNDATAKVLMISNEFRKPYMRPPLSKELWYTPNPNEDPIKDYRFKQWTGSERSLFFE 331
            ......::....:.::::.:.:...||.|..|||.|...|                   ..|...
  Rat   206 LVCAETLRQEGFSDRIVLCTLDRHLPYDRAKLSKSLDAQP-------------------EQLALR 251

  Fly   332 PDEFFIDPEDLDDNANGGIAVAQGFSVKKVDAQKRIVTLNDGYEISYDECLIATGCAPKNLPML- 395
            |.|||         ...||.:.....|..||.:.:.|...||:::.|.:.|:|.|.:||.|...
  Rat   252 PKEFF---------RAYGIEMLTEAQVVTVDVRNKKVVFKDGFKLEYSKLLLAPGSSPKTLTCKG 307

  Fly   396 RDAPPSVLEKVMVYRTPDDFDRLRKLAAEKRSITIVGNGFIGSELACSL---AH----------- 446
            :|     :|.|...|||:|.:|:.:| |..|:..:||.||:|.|:|..|   ||
  Rat   308 KD-----IENVFTIRTPEDANRVLRL-ARGRNAVVVGAGFLGMEVAAYLTEKAHSVSVVELEETP 366

  Fly   447 ---YSRENNGGKVYQVFQENANMSKVLPNYLSRWTTAKMEAQGVCVIPNASIRSAVRDETNLKLE 508
               :..|..|..:.::|:.|.      ..:..:...:::.||      ...::..|
  Rat   367 FRRFLGERVGRALMKMFENNR------VKFYMQTEVSELRAQ------EGKLQEVV--------- 410

  Fly   509 LNNGMTLMSDVVVVCVGCTPNTDLAGPSRLEVDRSLGGFVVNAELEAR-RNLYVAGDASCFFDPL 572
            |.:...|.:||.||.:|..|.|.....|.:.:| |.|...||..::.. ..::.||||..|  ||
  Rat   411 LKSSKVLRADVCVVGIGAVPATGFLRQSGIGLD-SRGFIPVNKMMQTNIPGVFAAGDAVTF--PL 472

  Fly   573 LGRR----RVEHHDHSVVSGRLAGENMTGAKK-----PYQHQSMFWSDLGPEIGYEGIGLVDSSL 628
            ..|.    .:.|...:...||:|.:||...:.     ||...:||    |..:.|.|.|
  Rat   473 AWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEINTVPYLWTAMF----GKSLRYAGYG------ 527

  Fly   629 PTVGVFALPSESATRVDQLSESSDSDVPETSTSSSQSSKSDAGASQDGVTCDPDEAGNYGKGVIF 693
                                |..|..:                     :..|.:|.    |.|.|
  Rat   528 --------------------EGFDDVI---------------------IQGDLEEL----KFVAF 547

  Fly   694 YLKNDKIVGILLWNLFNRIGLARTIINQNKKYDDLNEVAKLFEIHA 739
            |.|.|:::.:...|                 ||.:  |:|:.|:.|
  Rat   548 YTKGDEVIAVASMN-----------------YDPI--VSKVAEVLA 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AIF	NP_722765.2	Pyr_redox_2	257..573	CDD:285266	82/334 (25%)
		Pyr_redox	427..512	CDD:278498	18/101 (18%)
		AIF_C	591..720	CDD:291391	22/133 (17%)
Aifm3	XP_008767097.1	Rieske_AIFL_N	70..163	CDD:239560	21/107 (20%)
		Pyr_redox_2	194..492	CDD:400379	86/357 (24%)
		Reductase_C	511..>561	CDD:405449	17/104 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0446
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810