Protein Alignment AIF and wah-1

DIOPT Version :10

• Sequence 1: NP_722765.2
• Gene: AIF / 33390
• FlyBaseID: FBgn0031392
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: NP_499564.2
• Gene: wah-1 / 176635
• WormBaseID: WBGene00006937
• Length: 700
• Species: Caenorhabditis elegans
• Alignment Length: 536
• Identity: 180/536 - (33%)
• Similarity: 268/536 - (50%)
• Gaps: 75/536 - (13%)

  Fly   225 KAEAEEEERKRRLVAGLATSPPS----------SEDLPKHVPYLIIGGGTAAFSAFRAIKSNDAT 279
            ||:|.||:|..:     .:..||          |.|...|..|:|||.||||:.|..:|::..|.
 Worm   205 KADAVEEKRSEQ-----QSMKPSESTEENTTTTSADGLLHCEYVIIGSGTAAYYASLSIRAKQAE 264

  Fly   280 AKVLMISNEFRKPYMRPPLSKELWYTPNPNEDPIKDYRFKQWTGSERSLFFEPDEFFIDPEDLDD 344
            ||||||..|...||.|||||||||:  ..:|.......:...:|.:|.:|:|.|.||:.||||..
 Worm   265 AKVLMIGEEPELPYNRPPLSKELWW--YGDETSATKLAYTPLSGKKRDIFYEVDGFFVSPEDLPK 327

  Fly   345 NANGGIAVAQGFSVKKVDAQKRIVTLNDGYEISYDECLIATGCAPKNLPMLRDAPPSVLEKVMVY 409
            ..:||:|:.:|....|:..:.:.|.|.||..|.||:.|||||..||...:..:|.....:|:..:
 Worm   328 AVHGGVALLRGRKAVKICEEDKKVILEDGTTIGYDKLLIATGVRPKKEQVFEEASEEAKQKITYF 392

  Fly   410 RTPDDFDRLRKLAAEK--RSITIVGNGFIGSELACSLAHYSRENNGGKVYQVFQENANMSKVLPN 472
            ..|.||.|:.:..|:|  :.:||:|||.:.|||:.|:.....||  .:|:|||:|......:||.
 Worm   393 HYPADFKRVERGLADKSVQKVTIIGNGLLASELSYSIKRKYGEN--VEVHQVFEEKYPAEDILPE 455

  Fly   473 YLSRWTTAKMEAQGVCVIPNASIRSAVRDETNLKLELNNGMTLMSDVVVVCVGCTPNTDLAGPSR 537
            ::::.:...:...||.|.....:....:...|:.|:|::|..|.:|:|||..|..||:::...|.
 Worm   456 HIAQKSIEAIRKGGVDVRAEQKVEGVRKCCKNVVLKLSDGSELRTDLVVVATGEEPNSEIIEASG 520

  Fly   538 LEVDRSLGGFVVNAELEARRNLYVAGDASCFFDPLLGRRRVEHHDHSVVSGRLAGENMTGAK--- 599
            |::|..|||...:..|:...|::.||..:.|.|.:||.|||...:::.:|||||||||..|.
 Worm   521 LKIDEKLGGVRADKCLKVGENVWAAGAIATFEDGVLGARRVSSWENAQISGRLAGENMATAAADG 585

  Fly   600 ----KPYQHQSMFWSDLGPEIGYEGIGLVDSSLPTVGVFALPSESATRVDQLSESSDSDVPETST 660
                |.:.:|..|::...|.:....||..||||.||.|.|.|              |.|.|
 Worm   586 KSEGKAFWYQPSFFTKFAPHLHINAIGKCDSSLETVSVHAEP--------------DKDTP---- 632

  Fly   661 SSSQSSKSDAGASQDGVTCDPDEAGNYGKGVIFYLKND--KIVGILLWNLFN-RIGLARTIINQN 722
                                      ..|.|:||...:  .|||:||.|:|. .:.:||.||:..
 Worm   633 --------------------------LEKAVVFYKSKEDGSIVGVLLLNVFGPSLDVARRIIDDR 671

  Fly   723 KKYDDLNEVAKLFEIH 738
            ||.|:..|:||||.::
 Worm   672 KKVDEYKEIAKLFPLY 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AIF	NP_722765.2	NirB	256..719	CDD:440863	159/474 (34%)
		AIF_C	591..721	CDD:464279	39/139 (28%)
wah-1	NP_499564.2	NirB	242..686	CDD:440863	169/491 (34%)