Protein Alignment AIF and AIF

DIOPT Version :10

• Sequence 1: NP_722765.2
• Gene: AIF / 33390
• FlyBaseID: FBgn0031392
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: XP_061512173.1
• Gene: AIF / 1277908
• VectorBaseID: AGAMI1_014176
• Length: 750
• Species: Anopheles gambiae
• Alignment Length: 792
• Identity: 322/792 - (40%)
• Similarity: 450/792 - (56%)
• Gaps: 116/792 - (14%)

  Fly     1 MSIWGVRCLTQRFIR-QAYILA-----------------NRRLLGPVPQRSPPAYAPLRPAHSSL 47
            :::..|||:....:| :.::||                 |:.||....:       |.|...
Mosquito     7 VAVGNVRCVQPALVRIRKHVLAGGFTQTFGSRRWISVKVNQALLAKEAE-------PNRRRR--- 61

  Fly    48 YQMVKKRTLEARTKLQA--NKYPNHQVCVTKPSTTPPVEEYETAVEGAGVPAYANAQFQAHSQSE 110
             |.:|:|..|:......  .:.||....||....:..:......::....|:...|..:.|.
Mosquito    62 -QTLKEREAESNEPCSCVEEEGPNSSTIVTPCDESRRLPMMGELIQFPNDPSPYPAPPRRHI--- 122

  Fly   111 PLFKVGFADVKSVCSAKDVLKSDSAKLSTSQPVLDSCKATSPCEEFKRKRKETTCQPCDEDGTAP 175
            |:.:  |...|:|.:..|             |||.||:   .||..:.:.::...:..::...|.
Mosquito   123 PINR--FFQPKTVQTVPD-------------PVLSSCE---KCEREEEEEEDVVQEQTEQKAIAT 169

  Fly   176 GGGDGGDEECECRMKDLRLKCLLGALAALLAGGF-LAWF--------MTRDTDDSEAKKAEAEEE 231
            .||...........|......:|||: ||.|||. ||::        .....||::      |:.
Mosquito   170 TGGPTCPPPPPPPPKPSYTGYILGAI-ALTAGGLGLAYYNGLFDGPPPPTPVDDTK------EDA 227

  Fly   232 ERKRRLVAGLATSPPSSEDLPKHVPYLIIGGGTAAFSAFRAIKSNDATAKVLMISNEFRKPYMRP 296
            :||:|:.      |.||:|||||||||::|||||:.:|||||:.:|..|||:||:||...|||||
Mosquito   228 DRKKRIY------PASSKDLPKHVPYLLVGGGTASIAAFRAIRVHDPKAKVMMITNELEMPYMRP 286

  Fly   297 PLSKELWYTPNPNE-DPIKDYRFKQWTGSERSLFFEPDEFFIDPEDLDDNANGGIAVAQGFSVKK 360
            |||||||:  ||.| :|:|   |:||.|||||:|:||::::|||..|.|..|||:|||:|:.|.:
Mosquito   287 PLSKELWF--NPTEAEPLK---FRQWNGSERSIFYEPNDYYIDPSKLSDAPNGGVAVARGYEVHR 346

  Fly   361 VDAQKRIVTLNDGYEISYDECLIATGCAPKNLPMLRDAPPSVLEKVMVYRTPDDFDRLRKLAAEK 425
            :|...|...|.||.|||||:||||||..|||||:...||.:|.|:|.::::..||::|.....:.
Mosquito   347 LDVVNRKAILTDGTEISYDKCLIATGARPKNLPIFESAPRAVRERVTLFKSVYDFEQLSSQLQDG 411

  Fly   426 RSITIVGNGFIGSELACSLAHYSRENNGGK--VYQVFQENANMSKVLPNYLSRWTTAKMEAQGVC 488
            ..:.|||.||:||||||:|:. |.:....|  |:|:|.|..||:||||.|||.|||.::..:||.
Mosquito   412 NRVAIVGGGFLGSELACALSK-SEQTRKKKVEVFQLFHEGGNMAKVLPEYLSSWTTERLREEGVK 475

  Fly   489 VIPNASIRSAVRDETNLKLELNNGMTLMSDVVVVCVGCTPNTDLAGPSRLEVDRSLGGFVVNAEL 553
            |.|...:::.....:.|||.|.:...|:.|.|:|.||..||||||..|.||||...|||:|:|||
Mosquito   476 VWPKTQVKAVEMQGSKLKLTLMDDSVLLVDRVIVAVGSEPNTDLAKTSGLEVDSKNGGFLVDAEL 540

  Fly   554 EARRNLYVAGDASCFFDPLLGRRRVEHHDHSVVSGRLAGENMTGAKKPYQHQSMFWSDLGPEIGY 618
            .||.|::|||||:||:|...||||||||||::||||||||||.|..|||.|||||||||||.|.|
Mosquito   541 RARSNVFVAGDAACFYDTKFGRRRVEHHDHAIVSGRLAGENMVGLNKPYTHQSMFWSDLGPRISY 605

  Fly   619 EGIGLVDSSLPTVGVFA-------LPSESATRVDQLSESSDSD---------------VPETSTS 661
            |.|||:|||||||.|||       ..:.:|..|...:.|:||:               ||....|
Mosquito   606 EAIGLIDSSLPTVAVFAKRTAEEMSRAAAAAAVAVTAGSTDSEKLQAANANVNVDVKNVPAAGES 670

  Fly   662 SSQSSKSDAGASQDGVTCDPDEAGNYGKGVIFYLKNDKIVGILLWNLFNRIGLARTIINQNKKYD 726
            :.:.||...         :|::  ::.|||||||::.|:||::|||:|||:|.||.|::|:.:||
Mosquito   671 AKEQSKEQQ---------EPED--SFDKGVIFYLRDKKVVGLVLWNVFNRMGTARKILDQHTEYD 724

  Fly   727 DLNEVAKLFEIH 738
            |||||||||.:|
Mosquito   725 DLNEVAKLFNLH 736

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AIF	NP_722765.2	NirB	256..719	CDD:440863	245/487 (50%)
		AIF_C	591..721	CDD:464279	67/151 (44%)
AIF	XP_061512173.1	None